175204-38-3

Basic information

• Product Name: [3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOL-4-YL]METHANOL
• Synonyms: [3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOL-4-YL]METHANOL;BUTTPARK 98\50-55;3-(2,6-Dichlorophenyl)-4-(hydroxymethyl)-5-methylisoxazole
• CAS NO: 175204-38-3
• Molecular Formula: C₁₁H₉Cl₂NO₂
• Molecular Weight: 258.1
• Mol File: 175204-38-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 107 °C
• Boiling Point: 398.4°C at 760 mmHg
• Flash Point: 194.7°C
• Appearance: /
• Density: 1.397g/cm³
• Vapor Pressure: 4.62E-07mmHg at 25°C
• Refractive Index: 1.589
• CAS DataBase Reference: [3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOL-4-YL]METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOL-4-YL]METHANOL(175204-38-3)
• EPA Substance Registry System: [3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOL-4-YL]METHANOL(175204-38-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 175204-38-3(Hazardous Substances Data)

Usage

General Description

[3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOL-4-YL]METHANOL is a chemical compound that contains a 3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl group attached to a methanol molecule. The 3-(2,6-dichlorophenyl) group consists of a benzene ring with two chlorine atoms attached to it, and the 5-methylisoxazol-4-yl group is a five-membered heterocyclic ring containing both nitrogen and oxygen atoms. When combined with the methanol molecule, this compound may have applications in pharmaceuticals, agrochemicals, or other industries due to its potentially unique physical and chemical properties. Further research and testing would be required to fully understand the uses and effects of this compound.

InChI:InChI=1/C11H9Cl2NO2/c1-6-7(5-15)11(14-16-6)10-8(12)3-2-4-9(10)13/h2-4,15H,5H2,1H3

Upstream product

• 4402-83-9 SPB 06193 
• 6579-27-7 2,6-Dichloro-N-hydroxybenzenecarboximidoyl chloride 
• 6575-28-6 (1E)-2,6-dichlorobenzaldehyde oxime 
• 83-38-5 2,6-dichlorobenzaldehyde 
• 3919-76-4 3-(2,6-dichloro-phenyl)-5-methyl-isoxazole-4-carboxylic acid 

Downstream Products

• 287176-81-2 4-(bromomethyl)-3-(2,6-dichlorophenyl)-5-methylisoxazole 
• 303225-22-1 4-(chloromethyl)-3-(2,6-dichlorophenyl)-5-methylisoxazole 
• 919285-21-5 (4-{2-[3-(2,6-dichloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-ethoxy}-2-methyl-phenoxy)-acetic acid methyl ester 
• 870194-46-0 2-[3-(2,6-dichloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-ethanol 

Relevant articles and documents

COMPOUNDS FOR MODULATING FXR

Provided herein are compounds of Formula (I), a stereoisomer, enantiomer or a pharmaceutically acceptable salt thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X receptors (FXR).

3,4,5-Trisubstituted isoxazoles as novel PPARδ agonists: Part 1

We report the identification of a novel series of trisubstituted isoxazoles as PPAR activators from a high-throughput screen. A series of structural optimizations led to improved efficacy and excellent functional receptor selectivity for PPARδ. The isoxazoles represent a series of agonists which display a scaffold that lies outside the typical PPAR agonist motif.