175205-85-3

Basic information

• Product Name: 3,5-DIBROMOBENZAMIDE
• Synonyms: 3,5-DIBROMOBENZAMIDE;3,5-Dibromobenzamide 98%;3,5-Dibromobenzamide97%
• CAS NO: 175205-85-3
• Molecular Formula: C₇H₅Br₂NO
• Molecular Weight: 278.93
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;Amides;Carbonyl Compounds;Organic Building Blocks
• Mol File: 175205-85-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 187-190
• Boiling Point: 304.7 °C at 760 mmHg
• Flash Point: 138.1 °C
• Appearance: /
• Density: 1.985 g/cm³
• Vapor Pressure: 0.000861mmHg at 25°C
• Refractive Index: 1.639
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3,5-DIBROMOBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIBROMOBENZAMIDE(175205-85-3)
• EPA Substance Registry System: 3,5-DIBROMOBENZAMIDE(175205-85-3)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-22
• Safety Statements: 26-36
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 175205-85-3(Hazardous Substances Data)

Usage

General Description

3,5-dibromobenzamide is a chemical compound with the molecular formula C7H6Br2N2O. It is a white solid that is insoluble in water but soluble in organic solvents. 3,5-dibromobenzamide is used in the synthesis of various pharmaceuticals and agrochemicals. It is also used as an intermediate in the production of dyes and pigments. 3,5-dibromobenzamide has been identified as a potential environmental contaminant and may pose a risk to aquatic organisms. It is important to handle this compound with care and ensure proper disposal to prevent harm to the environment.

InChI:InChI=1/C7H5Br2NO/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3H,(H2,10,11)

Upstream product

• 145691-59-4 (3,5-dibromophenyl)methanol 
• 59785-43-2 3,5-dibromo-1-ethylbenzene 
• 4123-72-2 4-amino-3,5-dibromobenzoic acid 
• 618-58-6 3,5-dibromobenzoic acid 
• 23950-59-6 3,5-dibromobenzoyl chloride 

Downstream Products

• 1631160-91-2 3,5-bis[2-[3,4,5-tris(octyloxy)phenyl]ethynyl]phenyltetrazole 
• 1395084-11-3 5-(3,5-dibromophenyl)-2H-tetrazole 
• 97165-77-0 3,5-dibromobenzonitrile 
• 1312924-00-7 3-(2-(5-methylpyridin-2-yl)ethynyl)-5-bromobenzonitrile 
• 686768-53-6 3-(2-(2-methylthiazol-4-yl)ethynyl)-5-bromobenzonitrile 

Relevant articles and documents

Atomically Dispersed Ru on Manganese Oxide Catalyst Boosts Oxidative Cyanation

There is a strong incentive for environmentally benign and sustainable production of organic nitriles to avoid the use of toxic cyanides. Here we report that manganese oxide nanorod-supported single-site Ru catalysts are active, selective, and stable for oxidative cyanation of various alcohols to give the corresponding nitriles with molecular oxygen and ammonia as the reactants. The very low amount of Ru (0.1 wt %) with atomic dispersion boosts the catalytic performance of manganese oxides. Experimental and theoretical results show how the Ru sites enhance the ammonia resistance of the catalyst, bolstering its performance in alcohol dehydrogenation and oxygen activation, the key steps in the oxidative cyanation. This investigation demonstrates the high efficiency of a single-site Ru catalyst for nitrile production.

Potent mGluR5 antagonists: Pyridyl and thiazolyl-ethynyl-3,5-disubstituted- phenyl series

We report the synthesis of four series of 3,5-disubstituted-phenyl ligands targeting the metabotropic glutamate receptor subtype 5: (2-methylthiazol-4-yl) ethynyl (1a-j,), (6-methylpyridin-2-yl)ethynyl (2a-j), (5-methylpyridin-2-yl) ethynyl (3a-j,), and (pyridin-2-yl)ethynyl (4a-j,). The compounds were evaluated for antagonism of glutamate-mediated mobilization of internal calcium in an mGluR5 in vitro assay. All compounds were found to be full antagonists and exhibited low nanomolar to subnanomolar activity.