4123-72-2

Basic information

• Product Name: 4-Amino-3,5-dibromobenzoic acid
• Synonyms: 4-AMINO-3,5-DIBROMOBENZOIC ACID;BUTTPARK 35\03-07;4- aMino-3,5- twobroMo benzoic acid;3,5-Dibromo-4-aminobenzoicacid;RARECHEM AL BO 2270
• CAS NO: 4123-72-2
• Molecular Formula: C₇H₅Br₂NO₂
• Molecular Weight: 294.93
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 4123-72-2.mol
• Article Data: 4

Chemical Properties

• Melting Point: 330 °C (decomp)
• Boiling Point: 391.108 °C at 760 mmHg
• Flash Point: 190.336 °C
• Appearance: /
• Density: 2.159 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.7
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 4.08±0.10(Predicted)
• CAS DataBase Reference: 4-Amino-3,5-dibromobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-3,5-dibromobenzoic acid(4123-72-2)
• EPA Substance Registry System: 4-Amino-3,5-dibromobenzoic acid(4123-72-2)

Safety Data

• Hazardous Substances Data: 4123-72-2(Hazardous Substances Data)

Usage

General Description

4-Amino-3,5-dibromobenzoic acid is a chemical compound with the molecular formula C7H5Br2NO2. It is a derivative of benzoic acid, and it contains two bromine atoms and an amino group attached to the benzene ring. 4-Amino-3,5-dibromobenzoic acid is commonly used in organic synthesis and pharmaceutical research due to its versatile chemical reactivity and potential biological activities. It has been studied for its potential use as an antifungal and antimicrobial agent, as well as for its anti-inflammatory properties. Additionally, it has been used as a building block in the synthesis of various pharmaceutical compounds.

InChI:InChI=1/C7H5Br2NO2/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2H,10H2,(H,11,12)

Upstream product

• 10035-10-6 hydrogen bromide 
• 7722-84-1 dihydrogen peroxide 
• 150-13-0 4-amino-benzoic acid 
• 6311-37-1 4-amino-3-bromo-benzoic acid 
• 556-08-1 p-(acetylamino)benzoic acid 
• 619-45-4 4-methoxycarbonyl aniline 
• 3282-10-8 methyl 3,5-dibromo-4-aminobenzoate 
• 90484-59-6 4-acetylamino-3,5-dibromo-benzoic acid 

Downstream Products

• 3282-10-8 methyl 3,5-dibromo-4-aminobenzoate 
• 861303-23-3 3,5-dibromo-4-chlorobenzaldehyde 
• 123039-72-5 4-amino-3,5-dimethoxybenzoic acid 
• 175205-85-3 3,5-dibromobenzamide 
• 51329-15-8 methyl 3,5-dibromobenzoate 
• 23950-59-6 3,5-dibromobenzoyl chloride 
• 78626-85-4 2'''-nitro-m-septiphenyl 
• 78626-86-5 2'''-amino-m-septiphenyl 
• 70352-22-6 m-septiphenyl 
• 78626-83-2 2''-nitro-m-quinquephenyl 
• 78626-84-3 2''-amino-m-quinquephenyl 
• 16716-13-5 m-quinquephenyl 
• 4740-51-6 m-sexiphenyl 
• 13402-32-9 1,3-dibromo-2-nitrobenzene 

Relevant articles and documents

Method of catalytically synthesizing polybromo-aniline in water phase

The invention discloses a method of catalytically synthesizing polybromo-aniline in a water phase. The method comprises following steps: adding a catalytic amount of a free radical initiator, aniline derivatives, cheap and low-toxic bromine salts, and water into a reactor; carrying out reactions in a photocatalytic reaction instrument under power of 5W at a room temperature; after a while, extracting the reaction product by ethyl acetate, and carrying out recrystallization to obtain polybromo-aniline; wherein the free radical initiator is eosin, sodium persulfate, or potassium persulfate. The power of the incandescent lamp of the photocatalytic reaction instrument is 5W. The free radical initiator and bromine salts are cheap and easily available. The method is an ideal synthesis method of polybromo-aniline. Cheap and low-toxic bromine salts are used to replace liquid bromine. The cheap and easily available free radical initiator is used to replace unstable and explosive hydrogen peroxide. After 4 to 10 hours of reactions under the power of 5W, polybromo-aniline can be synthesized, the yield and the reaction selectivity are high, the byproducts are few, and the post treatment is simple.

Effect of structural factors and solvent nature in bromination of anilines

Reaction of electrophilic bromination of aniline containing various ortho, meta, and para substituents in the aromatic ring was studied. The optimal conditions for synthesis of mono-, di-, tri-, and tetrabromo derivatives of aniline and brominated analog of Aniline Black were found.