175227-87-9

Basic information

• Product Name: Trifluoro-methanesulfonic acid 1-(toluene-4-sulfonyl)-6,7-dihydro-1H-indol-4-yl ester
• Synonyms: Trifluoro-methanesulfonic acid 1-(toluene-4-sulfonyl)-6,7-dihydro-1H-indol-4-yl ester
• CAS NO: 175227-87-9
• Molecular Weight: 421.418
• Mol File: 175227-87-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Trifluoro-methanesulfonic acid 1-(toluene-4-sulfonyl)-6,7-dihydro-1H-indol-4-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Trifluoro-methanesulfonic acid 1-(toluene-4-sulfonyl)-6,7-dihydro-1H-indol-4-yl ester(175227-87-9)
• EPA Substance Registry System: Trifluoro-methanesulfonic acid 1-(toluene-4-sulfonyl)-6,7-dihydro-1H-indol-4-yl ester(175227-87-9)

Safety Data

• Hazardous Substances Data: 175227-87-9(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 35577-89-0 1-[(4-methylbenzene)sulfonyl]-4,5,6,7-tetrahydro-1H-indol-4-one 

Downstream Products

• 175227-88-0 1-(Toluene-4-sulfonyl)-6,7-dihydro-1H-indole-4-carboxylic acid methyl ester 
• 175227-90-4 1-(Toluene-4-sulfonyl)-4-trimethylsilanylethynyl-6,7-dihydro-1H-indole 
• 175227-93-7 1-[1-(Toluene-4-sulfonyl)-6,7-dihydro-1H-indol-4-yl]-3-trimethylsilanyl-propynone 
• 175227-98-2 Benzo[1,3]dioxol-5-yl-[1-(toluene-4-sulfonyl)-6,7-dihydro-1H-indol-4-yl]-methanone 
• 90481-75-7 4-(2-phenylethen-1-yl)-1-tosylindole 
• 31271-85-9 4-methoxycarbonyl-1-<(4-methylphenyl)sulfonyl>-1H-indole 
• 175227-97-1 4-Benzo[1,3]dioxol-5-yl-1-(toluene-4-sulfonyl)-6,7-dihydro-1H-indole 

Relevant articles and documents

Short step synthesis of 4-substituted indoles using palladium-catalyzed C-C bond forming reaction

Enol triflate of N-tosyl-4-oxo-tetrahydroindole (2) was a good precursor for a synthesis of 4-substituted indoles. Various functional groups were introduced to form corresponding indoles using palladium-catalyzed carbonylation and a cross-coupling reaction followed by dehydrogenation by palladium on charcoal.