17524-83-3Relevant academic research and scientific papers
Synthesis and crystal structures of some new 2-(diphenylamino)-4,5-disubstituted thiazole derivatives
Heydari, Reza,Shahrekipour, Fahimeh,Graiff, Claudia,Tahamipour, Batool
, p. 326 - 330 (2016)
The reactions of diphenylamine and benzoyl isothiocyanates with phenacyl bromide or methyl 2-bromoacetate in the presence of triethylamine yield 2,4,5-trisubstituted thiazole derivatives. The molecular structures of [2-(diphenylamino)-4-phenylthiazol-5-yl
Design, synthesis and identification of novel substituted 2-amino thiazole analogues as potential anti-inflammatory agents targeting 5-lipoxygenase
Sinha, Shweta,Doble, Mukesh,Manju
, p. 34 - 50 (2018/09/13)
Human 5-Lipoxygenase (5-LOX) is a key enzyme targeted for asthma and inflammation. Zileuton, the only drug against 5-LOX, was withdrawn from the market due to several problems. In the present study, the performance of rationally designed conjugates of thi
