175275-68-0Relevant academic research and scientific papers
Convenient synthesis of enantiomerically enriched (oxybutenyl)stannanes and their Lewis acid catalyzed homoaldol reactions
Paulsen, Holger,Graeve, Claudia,Hoppe, Dieter
, p. 141 - 144 (1996)
(E)-But-2-enyl N,N-diisopropylcarbamate (5), after deprotonation to its lithium/(-)-sparteine complex 6, yields with trialkyltin chlorides mixtures of the 3-oxy- and 1-oxy-substituted, enantiomerically enriched allylstannanes (S)-8 and (R)-9. (R)-8 is obt
Enantio- and diastereoselective synthesis of highly substituted acylcyclopropanes from homoaldol products by stereospecific homoallylic cyclization
Kalkofen, Rainer,Brandau, Sven,Uenaldi, Seda,Frohlich, Roland,Hoppe, Dieter
, p. 4571 - 4580 (2007/10/03)
Highly enantioenriched 4-hydroxy-1-alkenyl N,N-diisopropylcarbamates, easily available by asymmetric homoaldol reaction, cyclize by treatment with sodium hydride to form (1r,2t,3t)-configured 1-acylcyclopropanes with high diastereoselectivity. The decisiv
Synthesis of an enantioenriched α-carbamoyloxy-crotylboronate and its homoaldol reaction with aldehydes
Beckmann, Edith,Hoppe, Dieter
, p. 217 - 222 (2007/10/03)
Enantioenriched α-carbamoyloxy-crotylboronate 5 was prepared via the corresponding γ-stannylated carbamate. This boronate was then subjected to homoaldol reactions with aromatic and aliphatic aldehydes furnishing (Z)-anti-homoallylic alcohols in high diastereoselectivity and with complete chirality transfer.
Enantioselective synthesis of cyclopropanes by aldehyde homologation
Risatti, Christina A.,Taylor, Richard E.
, p. 6671 - 6672 (2007/10/03)
An efficient method for the enantioselective preparation of structurally diverse cyclopropanes has been developed. Sequential homoaldol coupling and activation steps result in a three-carbon homologation of an aldehyde to give a nonracemic, stereochemical
