175278-46-3 Usage
General Description
2-(cyclohexylthio)-5-nitrobenzaldehyde is a chemical compound with the molecular formula C13H15NO3S. It is a yellow crystalline solid with a distinctive odor. 2-(CYCLOHEXYLTHIO)-5-NITROBENZALDEHYDE is commonly used as a reagent in organic synthesis and as a building block in the production of various pharmaceuticals and agrochemicals. Its chemical structure contains a nitro group and a thioether, making it a versatile building block for the synthesis of a wide variety of organic compounds. Additionally, it has been studied for its potential biological activity, particularly as an antimicrobial and antitumor agent. However, its use and handling should be carried out with proper precautions, as it is toxic and may cause skin and eye irritation upon contact.
Check Digit Verification of cas no
The CAS Registry Mumber 175278-46-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,7 and 8 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 175278-46:
(8*1)+(7*7)+(6*5)+(5*2)+(4*7)+(3*8)+(2*4)+(1*6)=163
163 % 10 = 3
So 175278-46-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H15NO3S/c15-9-10-8-11(14(16)17)6-7-13(10)18-12-4-2-1-3-5-12/h6-9,12H,1-5H2
175278-46-3Relevant articles and documents
Nitroarylhydroxymethylphosphonic acids as inhibitors of CD45
Beers, Scott A.,Malloy, Elizabeth A.,Wu, Wei,Wachter, Michael P.,Gunnia, Uma,Cavender, Druie,Harris, Crafford,Davis, Janet,Brosius, Ruth,Pellegrino-Gensey, J. Lee,Siekierka, John
, p. 2203 - 2211 (2007/10/03)
A series of nitroarylhydroxymethylphosphonic acids was synthesized and evaluated as inhibitors of CD45. It was discovered that both the alpha hydroxy and nitro groups are essential for activity. Potency is enhanced by the addition of a large lipophilic group on the aryl ring adjacent to the phosphonic acid moiety. Kinetics studies have shown that these compounds are competitive inhibitors and thus bind at the active site of this enzyme.
