175431-36-4

Basic information

• Product Name: 3-(N-benzoylamino)pent-4-en-1-ol
• Synonyms: 3-(N-benzoylamino)pent-4-en-1-ol
• CAS NO: 175431-36-4
• Molecular Weight: 205.257
• Mol File: 175431-36-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(N-benzoylamino)pent-4-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(N-benzoylamino)pent-4-en-1-ol(175431-36-4)
• EPA Substance Registry System: 3-(N-benzoylamino)pent-4-en-1-ol(175431-36-4)

Safety Data

• Hazardous Substances Data: 175431-36-4(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 175431-85-3 3-amino-4-penten-1-ol 
• 284670-73-1 ethyl 3-(N-benzoylamino)pent-4-enoate 

Downstream Products

• 284670-74-2 3-(N-benzoylamino)pent-4-enal 

Relevant articles and documents

Intramolecular carbolithiation reactions for the preparation of azabicyclo [2.2.1] heptanes

Tin-lithium exchange and intramolecular carbolithiation (anionic cyclization) have been used to construct the three nitrogen-positional isomers of the azabicyclo[2.2.1]heptane ring system. The 7- azabicyclo[2.2.1]heptane ring system is accessed from either diastereomer of a 2,5-disubstituted pyrrolidine, via a chiral organolithium intermediate. The 2-azabicyclo[2.2.1]heptane ring system is formed stereoselectively in low yield by a tandem cyclization, together with the product from monocyclization. Better yields of the 2-aza ring system can be obtained using an alternative approach from a 2-tributylstannyl-4-allylpyrrolidine, despite the trans arrangement of the tin (and, hence, lithium) atom and the allyl unit. The 1-azabicyclo[2.2.1]heptane ring system is accessed in just three steps from 4-piperidone.