175602-46-7

Upstream product

• 153872-77-6 2-bromo-1,5-di-tert-butyl-3-methoxybenzene 

Downstream Products

• 175602-48-9 2-(2,4-Di-tert-butyl-6-methoxy-phenyl)-3-methyl-pyridine 
• 68039-43-0 1,3-di-tert-butyl-5-methoxybenzene 
• 367525-72-2 6-(2',4'-di-tert-butyl-6'-methoxyphenyl)pyridine-2-carboxyaldehyde 
• 367525-73-3 bis[6-(2',4'-di-tert-butyl-6'-methoxyphenyl)-2-pyridyl]methanol 
• 1067883-77-5 6-(2,4-di-tert-butyl-6-methoxyphenyl)quinoline 
• 184777-43-3 3,5-di-tert-butyl-2-(3'-methyl-2'-pyridyl)phenol 
• 367525-71-1 3,5-di-tert-butyl-2-(6'-bromo-2'-pyridyl)anisole 

Relevant academic research and scientific papers

Suzuki-Miyaura coupling of aryl tosylates catalyzed by an array of indolyl phosphine-palladium catalysts

A family of indolyl phosphine ligands was applied to Suzuki-Miyaura cross-coupling of aryl tosylates. Catalyst loading can be reduced to 0.2 mol % for coupling of nonactivated aryl tosylate. A challenging example for room temperature coupling is realized. The scope of this highly active Pd/L2 system can be extended to other boron nucleophiles, including trifluoroborate salts and boronate esters. The ligand structural comparisons toward the reactivity in tosylate couplings are also described.

A general palladium-catalyzed Suzuki-Miyaura coupling of aryl mesylates

(Chemical Equation Presented) Catalyze this! The first palladium-catalyzed Suzuki-Miyaura coupling of unactivated aryl mesylates is reported, with not only arylboronic acids, but also other organoboron nucleophiles (see picture; Z=B(OH)2, BF3K, BPin). The reaction conditions are compatible with various common functional groups (R1=alkyl, OMe, CHO, CO, CN, CO2R′, heteroaryl).