175650-09-6

Basic information

• Product Name: 2-benzyloxy-3,5-di-tert-butylbenzoic acid
• Synonyms: 2-benzyloxy-3,5-di-tert-butylbenzoic acid
• CAS NO: 175650-09-6
• Molecular Weight: 340.463
• Mol File: 175650-09-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-benzyloxy-3,5-di-tert-butylbenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyloxy-3,5-di-tert-butylbenzoic acid(175650-09-6)
• EPA Substance Registry System: 2-benzyloxy-3,5-di-tert-butylbenzoic acid(175650-09-6)

Safety Data

• Hazardous Substances Data: 175650-09-6(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 15018-03-8 methyl 3,5‐di‐tert-butyl‐2‐hydroxybenzoate 
• 853268-35-6 methyl 3,5-di-tert-butyl-2-benzyloxybenzoate 
• 175650-08-5 benzyl 2-benzyloxy-3,5-di-tert-butylbenzoate 

Downstream Products

• 853268-38-9 1,8-bis-(3,5-di-tert-butyl-2-benzyloxybenzamido)naphthalene 
• 853268-36-7 1,2-bis-(3,5-di-tert-butyl-2-benzyloxybenzamido)benzene 
• 853268-37-8 2,6-bis-(3,5-di-tert-butyl-2-benzyloxybenzamido)pyridine 
• 853268-41-4 1,8-bis-(3,5-di-tert-butyl-2-hydroxybenzamido)naphthalene 
• 853268-39-0 1,2-bis-(3,5-di-tert-butyl-2-hydroxybenzamido)benzene 
• 175650-10-9 2-benzyloxy-3,5-di-tert-butylbenzoyl chloride 

Relevant articles and documents

Synthesis of highly hindered polyanionic chelating ligands

Practical and efficient protocols to obtain highly hindered polyanionic chelating ligands based on bis-(3,5-di-tert-butyl-2-hydroxybenzamido) compounds are reported here. N-3,5-di-tert-Butylsalicyloyloxysuccinimide was treated with aliphatic diamines to form aliphatic hydrocarbon-linked bis-amides 4a-4g. Aromatic diamines required more powerful electrophile, thus the corresponding benzylated acid chloride was used to form aromatic hydrocarbon-linked bis-amides 8a-8d. The yields ranged from good to very good and showed that choosing the right acylating agent is a key point in this synthesis. All the compounds were characterized by elemental analysis, IR, MS and NMR.