1757-24-0

Usage

Uses

Used in Pharmaceutical Industry:
5-bromo-3-(bromomethyl)benzo[b]thiophene is used as an intermediate in organic synthesis for the production of various drugs and pharmaceuticals. Its unique structure and reactivity make it a valuable component in the synthesis of complex organic molecules with potential therapeutic applications.
Used in Organic Electronic Materials:
5-bromo-3-(bromomethyl)benzo[b]thiophene is utilized in the development of organic electronic materials due to its electronic properties. It serves as a building block in the synthesis of materials with potential applications in organic light-emitting diodes (OLEDs), organic solar cells, and other electronic devices.
Used in Heterocyclic Compounds Synthesis:
As a building block, 5-bromo-3-(bromomethyl)benzo[b]thiophene is employed in the synthesis of heterocyclic compounds. These compounds are important in various fields, including pharmaceuticals, agrochemicals, and materials science, due to their diverse chemical properties and potential applications.
It is crucial to handle 5-bromo-3-(bromomethyl)benzo[b]thiophene with caution and in accordance with proper safety protocols due to its reactive nature and potential health hazards.

InChI:InChI=1/C9H6Br2S/c10-4-6-5-12-9-2-1-7(11)3-8(6)9/h1-3,5H,4H2

Upstream product

• 1196-09-4 5-bromo-3-methylbenzo[b]thiophene 
• 17514-68-0 3-methyl-7-chlorobenzo[b]thiophene 
• 19075-36-6 6-bromo-3-methylbenzothiophene 
• 19075-35-5 4-bromo-3-methylbenzothiophene 
• 106-53-6 para-bromobenzenethiol 
• 94-36-0 dibenzoyl peroxide 
• 1200-12-0 1-(4-bromophenylthio)propan-2-one 

Downstream Products

• 23799-61-3 5-bromo-3-cyanomethylbenzo[b]thiophene 
• 22964-00-7 N-2-(5-bromobenzo[b]thiophen-3-yl)ethylamine hydrochloride 

Relevant academic research and scientific papers

Method for synthesizing 3 - halo methyl benzofuran compounds

The invention provides a method for efficiently synthesizing a 3-halomethylation benzofuran class compound by one step through a 2-propargyloxy aniline class compound. Compared with an existing method, the method can adapt to substrates for a wide range, the compound is convenient and easy to obtain, the reaction condition is mild, the operation is easy and convenient, and the reaction efficiency is high. By means of the method, metal salt compounds do not need to be added, and the production and processing for drugs are facilitated.

5-Halobenzothiophene analogues of melatonin: Synthesis and affinity for mt1 and MT2 receptors in man

A novel series of melatonin analogues based on the benzothiophene nucleus is described. In these compounds the methoxy group was replaced by electron-attracting groups such halogens (Br and Cl) with the aim of supplementing structure-affinity relationship

New serotonin 5-HT1F agonists

This invention provides novel 5-HT1Fagonists of formula where X, Y, Z,and R are defined in the specification, which are useful for the prevention and treatment of migraine and associated disorders.

Halogeno-Substituted 2- and 3-Methylbenzothiophenes: Use of 1H NMR Spectral Analysis and 1H Nuclear Overhauser Effect for Locating the Halogen Substituent

Thirty-seven halogeno-substituted 2- and 3-methyl-(or halogenomethyl)-benzothiophenes, including 17 new compounds, were prepared.The constitution of 14 of these was confirmed by full analysis (LAOCOON) of their 80 MHz 1H NMR spectra and by 1H NOE measurements.In this way a by-product from the preparation of 4- and 6-bromo-3-bromomethylbenzothiophenes was shown conclusively to be 5-bromo-3-bromomethylbenzothiophene.The 3-substituted benzothiophenes showed greater NOE enhancement factors at H-4 than at H-2 when the 3-methyl or halogenomethyl substituent was irradiated.

Benzo[b]thiophene derivatives. XXVIII. 5-Bromo-3-benzo[b]thienylalanine and derivatives

A potential inhibitor of gelation of sickle hemoglobin, 5-bromo-3-benzo[b]thienylalanine, has been synthesized along with several derivatives. Several hydrolytic pathways from the intermediate ethyl 5-bromo-3-benzo[b]thienylformamidomalonate have been exa