17580-20-0

Usage

Type of compound

Organic compound

Structural components

Chloropropanone group and biphenyl moiety

Industrial applications

Building block for the synthesis of other organic compounds

Research and development

Potential use in the development of new materials or pharmaceuticals

Chemical properties

Unique due to the presence of biphenyl and chloropropanone groups

Potential uses

Specific reactions or processes in industry and research

Upstream product

• 92-52-4 biphenyl 
• 625-36-5 2-chloropropionyl chloride 

Downstream Products

• 95942-94-2 4-p-biphenylyl-1,10-phenanthroline 
• 63472-09-3 1-Biphenyl-4-yl-3-(toluene-4-sulfonyl)-propan-1-one 
• 96710-07-5 4,7-di([1,1'-biphenyl]-4-yl)-1,10-phenanthroline 
• 94873-13-9 4-biphenyl-4-yl-8-nitro-quinoline 
• 95815-83-1 4-p-biphenylyl-8-aminoquinoline 
• 97802-12-5 4-p-biphenylyl-7-phenyl-1,10-phenanthroline 
• 97802-13-6 4-p-biphenylyl-7-p-bromophenyl-1,10-phenanthroline 
• 97802-14-7 4-p-biphenylyl-7-p-methoxyphenyl-1,10-phenanthroline 
• 3314-45-2 3-biphenyl-4-yl-1-phenyl-4,5-dihydro-1H-pyrazole 
• 1353347-98-4 3-(4-phenylphenyl)-4,5-dihydrofuran-2-carbaldehyde 
• 1353348-06-7 4-(4-phenylphenyl)-5,6-dihydro-2H-pyran-2-one 
• 1353347-82-6 2-ethynyl-2-(4-phenylphenyl)oxetan 

Relevant academic research and scientific papers

Bipiperidine substituted diphenyldione compound and uses thereof

The present invention discloses a novel bipiperidine substituted diphenyldione compound, which can inhibit the activity of cell histamine H3 receptors in a dose-dependent manner at a safe dose, and can acts as a histamine H3R antagonist to protect nerve c

Mn-Enabled Radical-Based Alkyl-Alkyl Cross-Coupling Reaction from 4-Alkyl-1,4-dihydropyridines

Highly efficient alkylation of β-chloro ketones and their derivatives was achieved by means of domino dehydrochlorination/Mn-enabled radical-based alkyl-alkyl cross-coupling reaction. In situ-generated α,β-unsaturated ketones and their analogues were identified as the reaction intermediates. Known bioactive compounds, such as melperone and azaperone, could be easily prepared from β-chloropropiophenone in two steps.

Cu(I)-catalyzed oxidative cyclization of alkynyl oxiranes and oxetanes

In the presence of a Cu(I) catalyst and a pyridine oxide, alkynyl oxiranes and oxetanes can be converted into functionalized five- or six-membered α,β-unsaturated lactones or dihydrofuranaldehydes. This new oxidative cyclization is proposed to proceed via an unusual allenyloxypyridinium intermediate.

Anti-inflammatory (halo-4-biphenylyl)-alkanolamines

Compounds of the formula wherein R is 4-biphenylyl or 4-phenoxyphenyl or a corresponding group monosubstituted or polysubstituted by one or more of F, Cl and Br; A is --CH(CH3)--CH2 --(CH2)n --, --C(CH3/su

Fenbufen, a new anti inflammatory analgesic: synthesis and structure activity relationships of analogs

100 analogs of fenbufen were prepared and tested using the carrageenan, polyarthritis, and UV erythema anti inflammatory tests and the 2 phenyl 1,4 benzoquinone writhing and inflamed paw pressure analgesic tests. Only 3 retained the same full spectrum of activity as fenbufen: dl 4 (4 biphenylyl) 4 hydroxybutyric acid, dl 4 (4 biphenylyl) 1,4 butanediol, and 4 biphenylacetic acid. Fenbufen had the same spectrum of activity as aspirin, phenylbutazone, and indomethacin in the 5 tests. In addition, dose response derived potencies show fenbufen more potent than aspirin and at least as potent as phenylbutazone in all 5 tests. Two related compounds were generally similar.