17595-84-5

Upstream product

• 188290-36-0 thiophene 
• 342-54-1 2-(methoxycarbonyl)benzenediazonium tetrafluoroborate 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 54663-78-4 tributyl(thien-2-yl)stannane 
• 6165-68-0 thiophene boronic acid 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 134-20-3 2-carbomethoxyaniline 
• 67-56-1 methanol 
• 6072-49-7 2-(2'-carboxyphenyl)thiophene 
• 17763-70-1 methyl 2-(trifluoromethylsulfonyloxy)benzoate 

Downstream Products

• 78515-62-5 4H-Indeno<1,2-b>thiophen-4-one Triphenylphosphazine 
• 194416-91-6 Methyl 2-(5'-formylthien-2'-yl)benzoate 
• 6072-49-7 2-(2'-carboxyphenyl)thiophene 
• 194416-95-0 Methyl 2-(5'-chloromethyl-2'-thienyl)benzoate 
• 194416-93-8 Methyl 2-(5'-hydroxymethylthien-2'-yl)benzoate 
• 194417-03-3 2-(5-Benzotriazol-1-ylmethyl-thiophen-2-yl)-benzoic acid methyl ester 
• 194416-98-3 2-[5-(2-Butyl-benzoimidazol-1-ylmethyl)-thiophen-2-yl]-benzoic acid methyl ester 
• 881690-46-6 4,4-di-p-tolyl-4H-indeno[1,2-b]thiophene 
• 773872-97-2 [2-(2-thienyl)phenyl]methanol 
• 5706-08-1 4H-Indeno<1,2-b>thiophen-4-one 
• 194416-92-7 o-(5-formyl-2-thienyl)benzonitrile 
• 97677-81-1 2-(2'-chloroformylphenyl)thiophene 
• 897446-34-3 N-(2-aminophenyl)-2-thiophen-2-ylbenzamide 

Relevant academic research and scientific papers

Palladium-catalyzed intramolecular aromatic C-H acylation of 2-arylbenzoyl fluorides

The catalytic intramolecular cyclization of acyl fluorides using a Pd(OAc)2/PCy3 system is described. A wide range of 2-arylbenzoyl fluoride derivatives can be used as fluorenone precursors and the reaction proceeds via an intramolecular coupling between aromatic C-H bonds with acyl C-F bonds. The reaction can be applied to the synthesis of indenofluorenedione derivatives and to the construction of other molecules with fivemembered rings.

Indene thiophthene and furan containing triarylamine compound and luminescent device

The invention provides an indene thiophthene and furan containing triarylamine compound. The compound has a following structural formula shown in the description. The compound has the advantages of higher thermal stability, high luminous efficiency, high

Synthesis of Novel 4,4-Dialkyl- and 4,4-Diarylindeno[1,2-b]Thiophenes and their 2-Bromo Derivatives

A series of new 4,4-dialkyl- and 4,4-diaryl-4H-indeno[1,2-b]thiophenes and their 2-bromo derivatives were synthesized and characterized. An economical one-pot method for the preparation of the key starting material 2-(2-thienyl)benzoic acid and improved p

Synthesis of heteroaryl compounds through cross-coupling reaction of aryl bromides or benzyl halides with thienyl and pyridyl aluminum reagents

An efficient method for synthesis of useful biaryl building blocks containing 2-thienyl, 3-thienyl, 2-pyridyl, and 3-pyridyl moieties was provided through cross-coupling reactions of aryl bromides or benzyl halides with heteroaryl aluminum reagents in the presence of Pd(OAc)2 and (o-tolyl)3P. The coupling reaction also worked efficiently with heteroaryl bromides affording series of heterobiaryl compounds. The reaction of phenylbromide with in situ prepared 3-pyridyl aluminum was demonstrated to afford the product 8a in high yield. Additionally, the catalytic system was also suited well for the coupling reaction of benzyl halides with pyridyl aluminum reagents to afford series of pyridyl-arylmethane.

AgONO-Assisted Direct C-H Arylation of Heteroarenes with Anilines

A novel copper-catalyzed C-H arylation of heteroarenes with anilines by an in situ diazonium reaction is established by using silver nitrite (AgONO) as an unconventional nitrosating reagent under acid-free conditions. It provides a complementary approach for the C-H arylation of electron-rich heteroarenes with aromatic amines affording a variety of heterobiaryls in moderate to good yields.

Pd-catalyzed C-H lactonization for expedient synthesis of biaryl lactones and total synthesis of cannabinol

A practical Pd(II)/Pd(IV)-catalyzed carboxyl-directed C-H activation/C-O cyclization to construct biaryl lactones has been developed. The synthetic utility of this new reaction was demonstrated in an atom-economical and operationally convenient total synthesis of the natural product cannabinol from commercially available starting materials, with the newly developed method used for two key steps.

Photochemical generation of thiophene analogs of 9-fluorenyl cations

The 9-fluorenyl cation is a member of the 4N Hueckel antiaromatic series of intermediates, first observed by time-resolved spectroscopy on UV photo-excitation of 9-fluorenol. Thiophene analogs of 9-fluorenol in which one of the annelated benzene rings is

Quaterthiophenes with terminal Indeno[1,2-b]thiophene units as p-type organic semiconductors

Quaterthiophenes 4T, Oct-4T, and Tol-4T based on a central 2,2′-bithiophene core α,ω-terminated with 4,4-unsubstituted and 4,4-disubstituted n-octyl or p-tolyl indeno[1,2-b]thiophene have been synthesized by Stille or Miyaura-Suzuki couplings. Compound 4T

Muscarinic Receptor Antagonists

Provided are muscarinic receptor antagonists, which can be useful in treating various diseases of the respiratory, urinary or gastrointestinal system mediated through muscarinic receptors. Also provided are processes for preparing compounds described herein, pharmaceutical compositions comprising compounds described herein, and methods for treating diseases mediated through muscarinic receptors.