175982-83-9 Usage
General Description
Tetrahydro-4-methoxy-2H-pyran-4-ol, also known as TAS-103, is a chemical compound that belongs to the class of pyran derivatives. It is a potential anti-cancer agent and has been studied for its ability to inhibit the growth of cancer cells. TAS-103 has shown promising results in preclinical studies, demonstrating its potential as a novel treatment for various types of cancer. Its unique structure and mechanism of action make it an attractive candidate for further development as a therapeutic agent. Research on TAS-103 continues to explore its potential for the treatment of cancer and other diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 175982-83-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,9,8 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 175982-83:
(8*1)+(7*7)+(6*5)+(5*9)+(4*8)+(3*2)+(2*8)+(1*3)=189
189 % 10 = 9
So 175982-83-9 is a valid CAS Registry Number.
175982-83-9Relevant articles and documents
Inhibitors of leukotriene B4. Synthesis and SAR of new β-enaminoester open-chain analogues of Zeneca ZD2138
Bird,Olivier
, p. 515 - 520 (2007/10/03)
A series of methoxy tetrahydropyranyl β-enaminoester has been discovered as inhibitors of LTB4 production. These are unusual open chain analogues of Zeneca ZD2138, the highly potent orally active 5-LO inhibitor under development for the treatment of asthma and rheumatoid arthritis. In vitro, compound 1a inhibited LTB4 formation in human whole blood with an IC50 of 0.04 μM. In inflamed exudate in the rat 1a inhibited formation of LTB4 with an oral ED50 3h after dosing of 3.0 mg/kg.
