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1760-43-6

2H-1,4-Benzodiazepin-2-one, 3-(benzoyloxy)-7-chloro-1,3-dihydro-5-phenyl- is a complex organic compound belonging to the benzodiazepine class. This molecule is characterized by a benzodiazepine core, which is a fused ring system consisting of a diazepine ring and a benzene ring. The specific compound in question features a 7-chloro substitution, indicating the presence of a chlorine atom at the 7th position. Additionally, it has a benzoyloxy group attached at the 3rd position, which is an ester derived from benzoic acid. The 5-phenyl substitution refers to a phenyl group (a benzene ring) attached at the 5th position of the benzodiazepine core. 2H-1,4-Benzodiazepin-2-one, 3-(benzoyloxy)-7-chloro-1,3-dihydro-5-phenyl- is significant in medicinal chemistry, as benzodiazepines are known for their anxiolytic, sedative, hypnotic, anticonvulsant, and muscle relaxant properties. The specific structure of 2H-1,4-Benzodiazepin-2-one, 3-(benzoyloxy)-7-chloro-1,3-dihydro-5-phenyl- may confer unique pharmacological properties, making it a subject of interest for potential therapeutic applications.

1760-43-6

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1760-43-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1760-43-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,6 and 0 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1760-43:
(6*1)+(5*7)+(4*6)+(3*0)+(2*4)+(1*3)=76
76 % 10 = 6
So 1760-43-6 is a valid CAS Registry Number.

1760-43-6Downstream Products

1760-43-6Relevant articles and documents

Synthesis of 3-Substituted-amino/aroyloxy-7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-ones as Possible Anxiolytics

Kulkarni, Y. D.,Abdi, s. H. R.,Sharma, V. L.,Dua, P. R.,Shanker, G.

, p. 425 - 426 (2007/10/02)

Ten new 3-substituted-amino/aroyloxy-7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-ones were synthesised and tested for their acute toxicity, effect on gross behaviour and anxiolytic activity using antihypoxia and antimetrazole tests in mice.At 1/5th ALD50, two compounds, one with a morpholino group and the other with a 4-methoxybenzoyloxy group at 3-position exhibited maximum antimetrazole activity similar to oxazepam and also produced significant increase of survival time in antihypoxia test which was comparable to oxazepam.

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