176217-62-2

Upstream product

• 879220-83-4 (3S,4S)-4-[N-acryloyl-N-(2,4-dimethoxybenzyl)amino]-3-[(tert-butyl)dimethylsiloxy]-5-phenylpent-1-ene 
• 99113-28-7 (3S,4S)-5-[(tert-butoxycarbonyl)amino]-3-hydroxy-5-phenyl-1-pentene 
• 879220-58-3 (5S,6S)-5-acetoxy-6-benzyl-5,6-dihydro-1-[(2,4-dimethoxy)benzyl]pyridin-2-one 
• 879220-57-2 (5S,6S)-6-benzyl-5,6-dihydro-1-[(2,4-dimethoxy)benzyl]-5-hydroxypyridin-2-one 
• 878440-96-1 (3S,4S)-3-[(tert-butyl)dimethylsilyloxy]-4-[N-(2-nitrobenzenesulfonyl)amino]-5-phenylpent-1-ene 
• 265996-19-8 (4S,5RS)-5-ethenyl-4-phenylmethyloxazolidin-2-one 
• 99113-28-7 4-<<(tert-butyloxy)carbonyl>amino>-3-hydroxy-5-phenyl-1-pentene 
• 66605-57-0 (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol 
• 72155-45-4 Boc-L-phenylalaninal 
• 880360-29-2 (S)-4-Benzyl-3-(toluene-4-sulfonyl)-5-vinyl-oxazolidin-2-one 
• 880360-34-9 6-benzyl-1-(toluene-4-sulfonyl)-3,6-dihydro-1H-pyridin-2-one 
• 879220-63-0 (6S)-6-benzyl-3,6-dihydro-1-[(2,4-dimethoxy)benzyl]pyridin-2-one 
• 201230-82-2 carbon monoxide 
• 1470-91-3 but-3-enoyl chloride 

Downstream Products

• 532936-17-7 (6S)-6-benzyl-3,6-dihydro-1-methylpyridin-2-one 

Relevant academic research and scientific papers

Unequivocal synthesis of (Z)-alkene and (E)-fluoroalkene dipeptide isosteres to probe structural requirements of the peptide transporter PEPT1

Described is a novel synthetic route for dipeptide isosteres containing (Z)-alkene and (E)-fluoroalkene units as cis-amide bond equivalents via organocopper-mediated reduction of γ-acetoxy- or γ,γ-difluoro- α,β-unsaturated-δ-lactams. The synthesized isost

Enantiospecific formation of 3,6-dihydro-1H-pyridin-2-ones: Low-pressure palladium-catalysed decarboxylative carbonylation of 3-tosyl-5-vinyloxazolidin- 2-ones

Palladium-catalysed decarboxylative carbonylation of 3-tosyl-5- vinyloxazolidin-2-ones 5 occurs at atmospheric pressure to give 1-tosyl-3,6-dihydro-1H-pyridin-2-ones 6. The reaction proceeds with no loss of enantiopurity and detosylation with sodium napht

New potential access to ethylenic pseudodipeptides through catalytic alkene metathesis

Dialkenenic amide 1 (R1 = CH2Ph, R2 = H) is readily converted, through ruthenium-catalysed metathetic ring closure, to ethylenic lactam 2, a close precursor of Z-ethylenic pseudodipeptide 3.