176236-88-7Relevant academic research and scientific papers
A general synthetic method for 2-substituted anthracenes
Dehaen, Wim,Corens, David,L'Abbe, Gerrit
, p. 201 - 203 (1996)
Anthracenes bearing a primary alkyl, ω-hydroxyalkyl, aryl or vinyl substituent at the 2-position are conveniently prepared by a copper-catalyzed Grignard reaction on 2,3-epoxy-1,2,3,4-tetrahydroanthracene, followed by dehydration - dehydrogenation of the resulting alcohols with tetrachloro-1,2-benzoquinone (o-chloranil).
Enantioselectivity in the reduction of tricyclic hydroaromatic ketones by baker's yeast
Fontana, Gabriele,Manitto, Paolo,Speranza, Giovanna,Zanzola, Simona
, p. 1381 - 1387 (2007/10/03)
Three benzo-2-tetralones were hydrogenated to the corresponding alcohols by non-fermenting baker's yeast. Satisfactory yields but modest enantioselectivities were observed. The prevalent enantioform of the benzo- 2-tetralol was found to be in agreement with the predictive abstract model previously proposed for the enzymatic hydrogenation of aromatic ring substituted 2-tetralones.
Naphtho and benzo analogues of the κ opioid agonist trans-(±)-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl] benzeneacetamide
Freeman,Michalson,D'Andrea,Baczynskyj,VonVoigtlander,Lahti,Smith,Lawson,Scahill,Mizsak,Szmuszkovicz
, p. 1891 - 1896 (2007/10/02)
Further elaboration on the structure-activity relationships in our U-50,488 series has revealed that benzologation of this cyclohexane-1,2-diamine derivative provides compounds which either maintain the interaction with the κ receptor (e.g. compounds 3a a
