176298-46-7

Basic information

• Product Name: 2-hydroxy-3-(4-methyl benzenesulfonylamino)-3-phenyl-propionic acid methyl ester
• Synonyms: 2-hydroxy-3-(4-methyl benzenesulfonylamino)-3-phenyl-propionic acid methyl ester
• CAS NO: 176298-46-7
• Molecular Weight: 349.408
• Mol File: 176298-46-7.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-3-(4-methyl benzenesulfonylamino)-3-phenyl-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-3-(4-methyl benzenesulfonylamino)-3-phenyl-propionic acid methyl ester(176298-46-7)
• EPA Substance Registry System: 2-hydroxy-3-(4-methyl benzenesulfonylamino)-3-phenyl-propionic acid methyl ester(176298-46-7)

Safety Data

• Hazardous Substances Data: 176298-46-7(Hazardous Substances Data)

Upstream product

• 127-65-1 chloroamine-T 
• 103-26-4 Methyl cinnamate 
• 7080-50-4 chloramine T trihydrate 
• 136561-53-0 (2R,3S)-2-hydroxy-3-amino-3-phenylpropionic acid 
• 32981-85-4 methyl (2R,3S)-3-benzoylamino-2-hydroxy-3-phenylpropanoate 
• 144-86-5 N-chloro-4-methylbenzenesulfonamide 
• 157240-36-3 (2R,3S)-3-phenylisoserine methyl ester 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 132201-33-3 (2R,3S)-N-benzoyl-3-phenylisoserine 
• 111524-98-2 (2S)-2-phenyl-2-(tosylamino)acetic acid 
• 111047-54-2 (S)-methyl 2-((4-methylphenyl)sulfonamido)-2-phenylacetate 
• 158109-81-0 cis-(2S,3S)-(+)-N-(p-toluenesulfonyl)-2-carbomethoxy-3-phenylaziridine 
• 433978-16-6 (2R,3S)-2-Hydroxy-3-phenyl-3-(toluene-4-sulfonylamino)-propionic acid 
• 136561-53-0 (2R,3S)-2-hydroxy-3-amino-3-phenylpropionic acid 

Relevant articles and documents

Synthesis and anti-HBV activity of novel 3′-N-phenylsulfonyl docetaxel analogs

Nine new 3′-N-phenylsulfonyl docetaxel analogs were synthesized in good yields from the key intermediate N-phenylsulfonyl oxazolidine via a six-step route. These analogs were tested for anti-hepatitis B virus (HBV) activity in vitro. Compounds 3e, 3g and 3j showed more potent inhibitory activity against HBeAg secretion than the positive control lamivudine. Further extensive SAR and mechanistic studies will be reported in due course.

A new approach to osmium-catalyzed asymmetric dihydroxylation and aminohydroxylation of olefins.

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Novel asymmetric C-C bond formation process promoted by Et2AlCl and its application to the stereoselective synthesis of unusual β-branched Baylis- Hillman adducts

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