176637-98-2 Usage
General Description
2-(2,4-Dichloro-5-fluorobenzoyl)-3-(4'-fluoro-phenylamino)-acrylic methylester is a chemical compound that is a combination of two different functional groups. It contains a 2,4-dichloro-5-fluorobenzoyl group and a 4'-fluoro-phenylamino-acrylic methylester group. 2-(2,4-Dichloro-5-fluorobenzoyl)-3-(4'-fluoro-phenylamino)-acrylic methylester is commonly used in pharmaceutical research and development due to its potential biological activity. It may have applications in the development of new drugs for various medical conditions. Additionally, its structural features make it a promising candidate for further investigation in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 176637-98-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,6,6,3 and 7 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 176637-98:
(8*1)+(7*7)+(6*6)+(5*6)+(4*3)+(3*7)+(2*9)+(1*8)=182
182 % 10 = 2
So 176637-98-2 is a valid CAS Registry Number.
176637-98-2Relevant articles and documents
Synthesis, molecular docking and biological evaluation of quinolone derivatives as novel anticancer agents
Li, Jie,Zheng, Tu-Cai,Jin, Yi,Xu, Jian-Guo,Yu, Jian-Gang,Lv, Yan-Wen
, p. 55 - 60 (2018/01/05)
A series of novel quinolone derivatives (8a-j) were synthesized, and their anticancer activities were tested in human cancer cell lines, human lung carcinoma cell (A549), human promyelocytic leukemia cell (HL-60), and human cervical cancer cell (Hela). Compound 8i was found to be 5-times more potent in cellkilling activity for cell lines A549, HL-60, and Hela than the positive control irinotecan or cisplatin, with IC50 of 0.009, 0.008 and 0.010 μM, respectively. The docking study revealed that compound 8i might have strong interactions with the active site of DNA-topoisomerase I.
