176637-98-2 Usage
Uses
Used in Pharmaceutical Research and Development:
2-(2,4-Dichloro-5-fluorobenzoyl)-3-(4'-fluoro-phenylamino)-acrylic methylester is utilized as a key component in the discovery and development of novel pharmaceutical agents. Its unique structural features and potential biological activity make it a promising candidate for the treatment of various medical conditions.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-(2,4-Dichloro-5-fluorobenzoyl)-3-(4'-fluoro-phenylamino)-acrylic methylester serves as a valuable compound for further investigation and exploration. Its structural attributes and potential interactions with biological targets offer opportunities for the design and synthesis of new drugs with improved efficacy and selectivity.
Used in Drug Development for Various Medical Conditions:
2-(2,4-Dichloro-5-fluorobenzoyl)-3-(4'-fluoro-phenylamino)-acrylic methylester is employed as a starting material or intermediate in the synthesis of drugs targeting a wide range of medical conditions. Its versatility and chemical properties allow for the development of therapeutic agents with novel mechanisms of action and potential for improved patient outcomes.
Used in the Synthesis of Organic and Metallic Nanoparticles for Drug Delivery:
2-(2,4-Dichloro-5-fluorobenzoyl)-3-(4'-fluoro-phenylamino)-acrylic methylester can be incorporated into the design of drug delivery systems, such as organic and metallic nanoparticles. These systems aim to enhance the bioavailability, delivery, and therapeutic efficacy of the compound, particularly in the context of cancer treatment and other challenging disease states.
Check Digit Verification of cas no
The CAS Registry Mumber 176637-98-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,6,6,3 and 7 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 176637-98:
(8*1)+(7*7)+(6*6)+(5*6)+(4*3)+(3*7)+(2*9)+(1*8)=182
182 % 10 = 2
So 176637-98-2 is a valid CAS Registry Number.
176637-98-2Relevant academic research and scientific papers
Synthesis, molecular docking and biological evaluation of quinolone derivatives as novel anticancer agents
Li, Jie,Zheng, Tu-Cai,Jin, Yi,Xu, Jian-Guo,Yu, Jian-Gang,Lv, Yan-Wen
, p. 55 - 60 (2018/01/05)
A series of novel quinolone derivatives (8a-j) were synthesized, and their anticancer activities were tested in human cancer cell lines, human lung carcinoma cell (A549), human promyelocytic leukemia cell (HL-60), and human cervical cancer cell (Hela). Compound 8i was found to be 5-times more potent in cellkilling activity for cell lines A549, HL-60, and Hela than the positive control irinotecan or cisplatin, with IC50 of 0.009, 0.008 and 0.010 μM, respectively. The docking study revealed that compound 8i might have strong interactions with the active site of DNA-topoisomerase I.
Process for the preparation of N-arylaminoacrylic acid derivatives and the use of N-arylaminoacrylic acid derivatives thus prepared for the preparation of 4-quinolone-3-carboxylic acid derivatives
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, (2008/06/13)
N-arylaminoacrylic acid derivatives are obtained in good yields and in high purities when benzoylacetic acid derivatives are reacted with N-arylimino ethers. The products thus prepared are used, in particular, for the preparation of 4-quinolone-3-carboxylic acid derivatives, which have an outstanding bactericidal action.
