103319-17-1

Basic information

• Product Name: METHYL 3-(2,4-DICHLORO-5-FLUOROPHENYL)-3-OXOPROPIONATE
• Synonyms: METHYL 3-(2,4-DICHLORO-5-FLUOROPHENYL)-3-OXOPROPIONATE
• CAS NO: 103319-17-1
• Molecular Formula: C₁₀H₇Cl₂FO₃
• Molecular Weight: 265.07
• Mol File: 103319-17-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: METHYL 3-(2,4-DICHLORO-5-FLUOROPHENYL)-3-OXOPROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-(2,4-DICHLORO-5-FLUOROPHENYL)-3-OXOPROPIONATE(103319-17-1)
• EPA Substance Registry System: METHYL 3-(2,4-DICHLORO-5-FLUOROPHENYL)-3-OXOPROPIONATE(103319-17-1)

Safety Data

• Hazardous Substances Data: 103319-17-1(Hazardous Substances Data)

Usage

General Description

Methyl 3-(2,4-dichloro-5-fluorophenyl)-3-oxopropionate is a chemical compound with the molecular formula C11H8Cl2FO3. It is a white to off-white crystalline powder that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. This chemical is known for its strong odor and is considered to be harmful if inhaled, swallowed, or exposed to skin. It is also considered to be an environmental hazard and should be handled and disposed of with caution.

Upstream product

• 704-10-9 2,4-dichloro-5-fluoroacetophenone 
• 616-38-6 carbonic acid dimethyl ester 
• 67-56-1 methanol 
• 111760-50-0 2,4-dichloro-5-fluorobenzoylacetic acid 

Downstream Products

• 129527-47-5 methyl-2,4-dichloro-5-fluoro-α-(4-fluoro-2-methylphenylhydrazono)benzoylacetate 
• 176637-98-2 methyl 3-[N-(4-fluorophenylamino)]-2-(2,4-dichloro-5-fluorobenzoyl)-acrylate 
• 129527-63-5 7-(3-ethylaminomethyl-1-pyrrolidinyl)-6-fluoro-1-(4-fluoro-2-methylphenyl)-1,4-dihydro-4-oxocinnoline-3-carboxylic acid 
• 114610-11-6 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxocinnoline-3-carboxylic acid 
• 129527-61-3 6-fluoro-1-(4-fluoro-2-methylphenyl)1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxocinnoline-3-carboxylic acid 
• 129527-59-9 6-fluoro-1-(4-fluoro-2-methylphenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)cinnoline-3-carboxylic acid 
• 114610-10-5 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-cinnoline-3-carboxylic acid 
• 129554-49-0 methyl 7-chloro-6-fluoro-1-(4-fluoro-2-methylphenyl)-1,4-dihydro-4-oxocinnoline-3-carboxylate 
• 129527-48-6 methyl 7-chloro-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxocinnoline-3-carboxylate 
• 114610-09-2 7-chloro-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxocinnoline-3-carboxylic acid 
• 129527-52-2 7-chloro-6-fluoro-1-(4-fluoro-2-methylphenyl)-1,4-dihydro-4-oxocinnoline-3-carboxylic acid 
• 402923-45-9 1-[4-(bis-benzyloxy-phosphoryloxy)-phenyl]-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid benzyl ester 
• 402923-41-5 6-fluoro-1-(4-methoxymethoxy-phenyl)-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid benzyl ester 
• 402923-44-8 6-fluoro-1-(4-hydroxy-phenyl)-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid benzyl ester 

Relevant articles and documents

Synthesis and crystal structure of methyl 2-(2,4-dichloro-5-fluorobenzoyl)- 3-(pyrimidin-2-ylamino)acrylate

Methyl 2-(2,4-dichloro-5-fluorobenzoyl)-3-(pyrimidin-2-ylamino)acrylate has been prepared. Its crystal structure is discussed. The compound crystallizes in the triclinic space group P-1 with a = 11.6259 (7) A, b = 11.8789 (7) A, c = 13.9206 (5) A, α = 68.

Preparation of halogenated aroylacetic acid esters

A process for the preparation of a halogenated aroylacetic acid ester of the formula STR1 in which R is alkyl with 1-6 carbon atoms, X and X2 each independently is halogen, and X1 and X3 each independently is hydrogen or h