1767-46-0

Basic information

• Product Name: (S)-(+)-4-METHYL-1-HEXANOL
• Synonyms: (S)-(+)-4-METHYL-1-HEXANOL 98+%;(S)-(+)-4-Methyl-1-hexanol;(S)-4-Methylhexan-1-ol;(S)-(+)-4-METHYL-1-HEXANOL
• CAS NO: 1767-46-0
• Molecular Formula: C₇H₁₆O
• Molecular Weight: 116.2
• Product Categories: Building Blocks for Liquid Crystals;Chiral Building Blocks;Chiral Compounds (Building Blocks for Liquid Crystals);Functional Materials;Glycidyl Compounds, etc. (Chiral);Synthetic Organic Chemistry
• Mol File: 1767-46-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 126 °C / 140mmHg
• Flash Point: 61.8 °C
• Appearance: /
• Density: 0.83
• Refractive Index: 7.5 ° (C=neat)
• PKA: 15.20±0.10(Predicted)
• CAS DataBase Reference: (S)-(+)-4-METHYL-1-HEXANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-4-METHYL-1-HEXANOL(1767-46-0)
• EPA Substance Registry System: (S)-(+)-4-METHYL-1-HEXANOL(1767-46-0)

Safety Data

• Hazardous Substances Data: 1767-46-0(Hazardous Substances Data)

Usage

General Description

(S)-(+)-4-Methyl-1-hexanol is an organic compound with a pleasant, sweet, and fruity aroma. It is classified as a secondary alcohol and is commonly used as a fragrance ingredient in products such as perfumes, lotions, and cosmetics. This chemical is also utilized in the production of flavors for food and beverages. Additionally, (S)-(+)-4-Methyl-1-hexanol can be used as a solvent in various industrial applications, such as in the manufacturing of paints, coatings, and cleaning products. It is important to handle this chemical with care as it may cause irritation to the skin, eyes, and respiratory system upon exposure.

Upstream product

• 6210-80-6 ethyl (S)-4-methylhexanoate 
• 50-00-0 formaldehyd 
• 41248-91-3 (S)-(+)-3-methylpentyl chloride 
• 534-00-9 (S)-2-methylbutyl bromide 
• 60711-13-9 (S)-2,6-dimethyloct-2-ene 
• 2385-77-5 (R)-Citronellal 
• 1580449-05-3 benzyl (4S)-4-methylhexyl ether 
• 130129-23-6 (4R,6R)-6-(benzyloxymethyl)-4-methyltetrahydro-2H-pyran-2-one 
• 1580448-84-5 (3S,5R)-6-(benzyloxy)-3-methylhexane-1,5-diol 
• 18951-85-4 (R)-citronellic acid 
• 38261-81-3 (S)-2-methylbutyl tosylate 
• 1565-80-6 (2S)-2-methyl-1-butanol 
• 132403-92-0 (S)-2-(2-methylbutyl)malonic acid 
• 6210-82-8 diethyl S-(+)-2-methyl-1-butyl malonate 

Downstream Products

• 1561-11-1 4-methylhexanoic acid 
• 7492-90-2 (+)-(S)-methyl 4-methylhexanoate 
• 3350-10-5 N-[(R)-4-benzyloxycarbonylamino-2-((S)-6-methyl-octanoylamino)-butyryl]-L_s-threonine methyl ester 
• 120581-48-8 N-[(R)-4-benzyloxycarbonylamino-2-((S)-6-methyl-octanoylamino)-butyryl]-L_s-threonine 
• 504-99-4 (6S)-6-methyloctanoic acid 
• 333718-46-0 (2R,6S)-N-[(1S,2S)-N-(2-hydroxy-1-methyl-2-phenyl)ethyl]-N,2,6-trimethyloctanamide 
• 333718-31-3 (2S,6S)-N-[(1R,2R)-N-(2-hydroxy-1-methyl-2-phenyl)ethyl]-N,2,6-trimethyloctanamide 
• 864380-52-9 (2RS,4'S)-2-(4-methylhexyl)cyclohexanone 
• 70200-32-7 (S)-4-Methylhexyl p-toluenesulfonate 
• 117814-37-6 5-(4-Decyloxy-phenyl)-2-((S)-4-methyl-hexyloxy)-pyrimidine 
• 117814-33-2 2-((S)-4-Methyl-hexyloxy)-5-(4-octyl-phenyl)-pyrimidine 
• 53353-01-8 (S)-1-bromo-4-methylhexane 

Relevant articles and documents

L-(-)-menthol in the synthesis of key synthons for optically active methyl-branched insect pheromones

A synthesis of optically active 4S-methylhexanal, 1-bromo-3S-methylheptane, and 1-bromo-3S-methylundecane, which are key synthons for several methyl-branched insect pheromones, that is based on chemically selective transformations of 6-tosyloxy- and 6-iodoisopropyl-4R-methylhexanoates that are available from L-(-)-menthol was proposed. 2005 Springer Science+Business Media, Inc.

Novel Caprolactones from a Marine Streptomycete

Two new caprolactones, (R)-10-methyl-6-undecanolide (1) and (6R,10S)-10-methyl-6-dodecanolide (2), were identified in the lipid extract of a marine streptomycete (isolate B6007). Their structures were proposed on the basis of GC-MS experiments and proved by synthesis. The absolute configuration of the compounds was established by comparison of the natural and synthetic stereoisomers using chiral gas chromatography. These caprolactones show a moderate phytotoxicity and a promising activity against cancer cells with concomitant low general cytotoxicity.

Highly regio-, (E)-stereo-, and diastereoselective SN2′ addition of organocuprates to chiral allylic cyclic carbonates

Reaction of the cyclic carbonates of acyclic vinyl diols with RCu(CN)Li· BF3, RCu(CN)MgBr·BF3, or RMgBr·CuI (cat) in THF at -78°C proceeded in SN2′ fashion and resulted in the formation of alkylated (E)-allylic alcohols wi