17683-99-7

Usage

Uses

Used in Pharmaceutical and Agrochemical Development:
(Z)-3-(4-NITRO-PHENYL)-3-PHENYL-ACRYLIC ACID is used as a key intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into various drug molecules, potentially enhancing their therapeutic properties and effectiveness.
Used in Organic Chemistry Research:
(Z)-3-(4-NITRO-PHENYL)-3-PHENYL-ACRYLIC ACID is used as a reagent in organic chemistry reactions, facilitating the creation of new chemical entities and contributing to the advancement of chemical research.
Used in Materials Science:
(Z)-3-(4-NITRO-PHENYL)-3-PHENYL-ACRYLIC ACID may be utilized in the development of novel materials, potentially offering unique properties or improvements in existing material systems due to its specific molecular structure.

Upstream product

• 1144-74-7 4-nitrobenzophenone 
• 21320-81-0 ethyl 3-(4-nitrophenyl)-3-phenylacrylate 
• 365426-14-8 ethyl (2Z)-3-(4-nitrophenyl)-3-phenylprop-2-enoate 

Downstream Products

• 1437756-97-2 7-nitro-4-phenyl-2H-chromen-2-one 
• 188913-63-5 1-[4-(2-methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-piperidin-1-yl]-3-(4-nitro-phenyl)-3-phenyl-propenone 
• 188913-58-8 (E)-2-hydroxy-5-[[4-[3-[4-[(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)methyl]-1-piperidinyl]-3-oxo-1-phenyl-1-propenyl]phenyl]azo]benzoic acid 
• 188913-58-8 (Z)-2-hydroxy-5-[[4-[3-[4-[(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)methyl]-1-piperidinyl]-3-oxo-1-phenyl-1-propenyl]phenyl]azo]benzoic acid 
• 179173-99-0 cis-1-[[1-[3-(4-Aminophenyl)-3-phenylpropenoyl]-4-piperidyl]methyl]-1H-2-methylimidazo[4,5-c]pyridine 
• 179173-55-8 UR 12715 
• 21316-11-0 N--p-nitro-α-phenyl-zimtsaeureamid 
• 21316-16-5 p-Nitro-β-phenyl-zimtsaeure-p-fluorsulfonyl-anilid 
• 179173-54-7 1-[4-(2-methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-piperidin-1-yl]-3-(4-nitro-phenyl)-3-phenyl-propenone 
• 1569819-45-9 (R,Z)-4-(1-phenyl-3-((1-phenylethyl)amino)prop-1-en-1-yl)aniline 
• 1569819-37-9 (R,Z)-3-(4-nitrophenyl)-3-phenyl-N-(1-phenylethyl)prop-2-en-1-amine 
• 1569821-68-6 (Z)-3-(4-nitrophenyl)-3-phenylacrylaldehyde 

Relevant academic research and scientific papers

FENDILINE DERIVATIVES AND METHODS OF USE THEREOF

Disclosed herein are novel derivatives of fendiline, including compounds of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising these derivative compounds. Methods and intermediates useful for making the derivatives, and methods of using the derivatives, for example, for the inhibition of K-Ras plasma membrane localization, and compositions thereof, including for the treatment of cancer, are also provided.

Synthesis of coumarins via PIDA/I2-mediated oxidative cyclization of substituted phenylacrylic acids

A variety of functionalized coumarins were synthesized from substituted phenylacrylic acids via PIDA/I2-mediated and irradiation-promoted oxidative carbon-oxygen bond formation. Our studies show that the oxygen in the pendant carboxylic acid group cyclizes favorably to the aryl ring that is cis to it. The main advantages of this method include good functional group tolerance and the transition-metal-free characteristic. The Royal Society of Chemistry 2013.

Novel azo derivatives as prodrugs of 5-aminosalicylic acid and amino derivatives with potent platelet activating factor antagonist activity

This paper describes the synthesis of a series of azo compounds able to deliver 5-aminosalicylic acid (5-ASA) and a potent platelet activating factor (PAF) antagonist in a colon-specific manner for the purpose of treating ulcerative colitis. We found it p

Diphenylpropenamides as SRS-A antagonists

Certain new diphenylpropenamides having a carboxyalkanamido or a carboxyalkenamido group on one of the phenyl rings and their use for antagonizing the spasmogenic activity of the slow-reacting substance of anaphylaxis (SRS-A) in a human subject. In particular, the compounds of the invention are useful for preventing and treating certain obstructive airways diseases, notably allergic bronchial asthma, allergic rhinitis and certain skin disorders, in human subjects.