1569821-68-6

Basic information

• Product Name: (Z)-3-(4-nitrophenyl)-3-phenylacrylaldehyde
• Synonyms: (Z)-3-(4-nitrophenyl)-3-phenylacrylaldehyde
• CAS NO: 1569821-68-6
• Molecular Weight: 253.257
• Mol File: 1569821-68-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (Z)-3-(4-nitrophenyl)-3-phenylacrylaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-(4-nitrophenyl)-3-phenylacrylaldehyde(1569821-68-6)
• EPA Substance Registry System: (Z)-3-(4-nitrophenyl)-3-phenylacrylaldehyde(1569821-68-6)

Safety Data

• Hazardous Substances Data: 1569821-68-6(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 636-98-6 p-nitrobenzene iodide 
• 17683-99-7 (Z)-3-(4-nitrophenyl)-3-phenylpropenoic acid 
• 365426-14-8 ethyl (2Z)-3-(4-nitrophenyl)-3-phenylprop-2-enoate 
• 1144-74-7 4-nitrobenzophenone 
• 13632-64-9 1-(4-nitrophenyl)-1-phenyl-2-propyn-1-ol 

Downstream Products

• 1569819-37-9 (R,Z)-3-(4-nitrophenyl)-3-phenyl-N-(1-phenylethyl)prop-2-en-1-amine 
• 1569819-45-9 (R,Z)-4-(1-phenyl-3-((1-phenylethyl)amino)prop-1-en-1-yl)aniline 

Relevant articles and documents

Palladium-Catalyzed Cascade Saegusa–Heck Reaction: Synthesis of β,β-Diarylacroleins from Arylpropanals and Aryl Iodides

An efficient and convenient Pd-catalyzed Saegusa–Heck cascade protocol was developed, and its potential use in the synthesis of symmetrical and unsymmetrical β,β-diarylacroleins in moderate to high yields was investigated.

FENDILINE DERIVATIVES AND METHODS OF USE THEREOF

Disclosed herein are novel derivatives of fendiline, including compounds of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising these derivative compounds. Methods and intermediates useful for making the derivatives, and methods of using the derivatives, for example, for the inhibition of K-Ras plasma membrane localization, and compositions thereof, including for the treatment of cancer, are also provided.