365426-14-8

Basic information

• Product Name: ethyl (2Z)-3-(4-nitrophenyl)-3-phenylprop-2-enoate
• Synonyms: ethyl (2Z)-3-(4-nitrophenyl)-3-phenylprop-2-enoate
• CAS NO: 365426-14-8
• Molecular Weight: 297.31
• Mol File: 365426-14-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: ethyl (2Z)-3-(4-nitrophenyl)-3-phenylprop-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2Z)-3-(4-nitrophenyl)-3-phenylprop-2-enoate(365426-14-8)
• EPA Substance Registry System: ethyl (2Z)-3-(4-nitrophenyl)-3-phenylprop-2-enoate(365426-14-8)

Safety Data

• Hazardous Substances Data: 365426-14-8(Hazardous Substances Data)

Upstream product

• 100-00-5 4-chlorobenzonitrile 
• 4192-77-2 ethyl cinnamate 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 1144-74-7 4-nitrobenzophenone 
• 4071-88-9 trimethylsilanyl-acetic acid ethyl ester 

Downstream Products

• 179173-55-8 UR 12715 
• 179173-54-7 1-[4-(2-methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-piperidin-1-yl]-3-(4-nitro-phenyl)-3-phenyl-propenone 
• 188913-58-8 (Z)-2-hydroxy-5-[[4-[3-[4-[(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)methyl]-1-piperidinyl]-3-oxo-1-phenyl-1-propenyl]phenyl]azo]benzoic acid 
• 1437756-97-2 7-nitro-4-phenyl-2H-chromen-2-one 
• 1569819-45-9 (R,Z)-4-(1-phenyl-3-((1-phenylethyl)amino)prop-1-en-1-yl)aniline 
• 1569819-37-9 (R,Z)-3-(4-nitrophenyl)-3-phenyl-N-(1-phenylethyl)prop-2-en-1-amine 
• 1569821-68-6 (Z)-3-(4-nitrophenyl)-3-phenylacrylaldehyde 
• 17683-99-7 (Z)-3-(4-nitrophenyl)-3-phenylpropenoic acid 

Relevant articles and documents

FENDILINE DERIVATIVES AND METHODS OF USE THEREOF

Disclosed herein are novel derivatives of fendiline, including compounds of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising these derivative compounds. Methods and intermediates useful for making the derivatives, and methods of using the derivatives, for example, for the inhibition of K-Ras plasma membrane localization, and compositions thereof, including for the treatment of cancer, are also provided.

Novel azo derivatives as prodrugs of 5-aminosalicylic acid and amino derivatives with potent platelet activating factor antagonist activity

This paper describes the synthesis of a series of azo compounds able to deliver 5-aminosalicylic acid (5-ASA) and a potent platelet activating factor (PAF) antagonist in a colon-specific manner for the purpose of treating ulcerative colitis. We found it p