176894-58-9Relevant articles and documents
C-terminal 1-aminoethyltetrazole-containing oligopeptides as novel alanine racemase inhibitors
Anderson, Rosaleen J.,Gray, Mark,Kondacs, Laszlo A.,Marrs, Emma C. L.,Orenga, Sylvain,Perry, John D.
, (2020/03/19)
In clinical culture media inoculated with patient samples, selective inhibition of commensal bacteria is essential for accurate diagnosis and effective treatment, as they can mask the presence of pathogenic bacteria. The alanine analogue, 1-aminoethyltetr
P2X3, RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN
-
Page/Page column 67, (2010/11/18)
The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X3 receptor subunit modulator.
Design and synthesis of cyclopenta[g]quinazoline-based antifolates as inhibitors of thymidylate synthase and potential antitumor agents
Bavetsias, Vassilios,Marriott, Jonathan H.,Melin, Camille,Kimbell, Rosemary,Matusiak, Zbigniew S.,Boyle, F. Thomas,Jackman, Ann L.
, p. 1910 - 1926 (2007/10/03)
Following the development of raltitrexed, the synthesis of nonpolyglutamatable inhibitors of TS that do not use the reduced folate carrier (RFC) for cellular entry should provide compounds which overcome mechanisms of resistance to folate-based inhibitors