34276-31-8

Basic information

• Product Name: benzyl N-[(1R)-1-(1H-1,2,3,4-tetrazol-5-yl)ethyl]carbamate
• Synonyms: benzyl N-[(1R)-1-(1H-1,2,3,4-tetrazol-5-yl)ethyl]carbamate
• CAS NO: 34276-31-8
• Molecular Weight: 247.257
• Mol File: 34276-31-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: benzyl N-[(1R)-1-(1H-1,2,3,4-tetrazol-5-yl)ethyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl N-[(1R)-1-(1H-1,2,3,4-tetrazol-5-yl)ethyl]carbamate(34276-31-8)
• EPA Substance Registry System: benzyl N-[(1R)-1-(1H-1,2,3,4-tetrazol-5-yl)ethyl]carbamate(34276-31-8)

Safety Data

• Hazardous Substances Data: 34276-31-8(Hazardous Substances Data)

Upstream product

• 26607-51-2 N-benzyloxycarbonyl-D-alanine 
• 28819-05-8 N-benzyloxycarbonyl-D-alanine methyl ester 
• 151378-81-3 benzyl [(1R)-2-amino-1-methyl-2-oxoethyl]carbamate 
• 102988-93-2 C₁₆H₂₁NO₆ 
• 176894-58-9 (2R)-2-(benzyloxycarbonylamino)propionitrile 

Relevant articles and documents

Carboxylic acid bioisosteres of γ-linked dipeptide analogues of the folate-based thymidylate synthase (TS) inhibitor, 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583)

Tetrazole carboxylic acid bioisosteres of γ-linked dipeptide derivatives of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583), a folate-based inhibitor of thymidylate synthase (TS), were synthesised by multistep routes starti

Design and synthesis of cyclopenta[g]quinazoline-based antifolates as inhibitors of thymidylate synthase and potential antitumor agents

Following the development of raltitrexed, the synthesis of nonpolyglutamatable inhibitors of TS that do not use the reduced folate carrier (RFC) for cellular entry should provide compounds which overcome mechanisms of resistance to folate-based inhibitors