176901-48-7

Upstream product

• 91971-58-3 ethyl 2,3-dimethoxy benzoate 
• 91-16-7 1,2-dimethoxybenzene 

Downstream Products

• 181016-77-3 2‐(5‐bromo‐2,3‐dimethoxyphenyl)propan‐2‐ol 
• 181016-76-2 6-[2-(2-Bromomethyl-5-isopropyl-3,4-dimethoxy-phenyl)-ethyl]-7,7-dimethyl-1,4-dioxa-spiro[4.5]decane 
• 181016-83-1 {6-[2-(7,7-Dimethyl-1,4-dioxa-spiro[4.5]dec-6-yl)-ethyl]-4-isopropyl-2,3-dimethoxy-phenyl}-methanol 
• 176901-52-3 6-[2-(3-Isopropyl-4,5-dimethoxy-phenyl)-ethyl]-7,7-dimethyl-1,4-dioxa-spiro[4.5]decane 
• 176901-51-2 2-[2-(3-isopropyl-4,5-dimethoxyphenyl)ethyl]-5,5-dimethyl-cyclohexan-1-one 
• 181016-82-0 5-[2-(3-isopropyl-4,5-dimethoxyphenyl)ethyl]-5,5-dimethyl-2-cyclohexen-1-one 
• 181016-81-9 5-(2-Iodo-ethyl)-1-isopropyl-2,3-dimethoxy-benzene 
• 181016-79-5 2-(3-isopropenyl-4,5-dimethoxyphenyl)ethanol 
• 181016-80-8 2-(3-isopropyl-4,5-dimethoxyphenyl)ethanol 
• 181016-78-4 5-bromo-1-isopropenyl-2,3-dimethoxybenzene 

Relevant academic research and scientific papers

The first total synthesis of (±)-demethyl salvicanol

Demethyl salvicanol, a novel rearranged 9(10 → 20)-abeo-8, 11, 13-triene diterpene, has been synthesized for the first time. The zinc-promoted coupling reaction of benzyl bromide with ketone and the alkylation of ketone with iodide are the key steps.

BRIDGED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS

The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts or solvates thereof, wherein all the variables are as defined herein. These compounds modulate the activity of farnesoid X receptor