181016-77-3

Upstream product

• 153390-68-2 2-<2,3-dimethoxyphenyl>-propan-2-ol 
• 91971-58-3 ethyl 2,3-dimethoxy benzoate 
• 91-16-7 1,2-dimethoxybenzene 
• 2150-42-7 methyl 2,3-dimethoxybenzoate 
• 75-16-1 methylmagnesium bromide 
• 176901-48-7 ethyl 5-bromo-2,3-dimethoxybenzoate 

Downstream Products

• 181016-76-2 6-[2-(2-Bromomethyl-5-isopropyl-3,4-dimethoxy-phenyl)-ethyl]-7,7-dimethyl-1,4-dioxa-spiro[4.5]decane 
• 181016-83-1 {6-[2-(7,7-Dimethyl-1,4-dioxa-spiro[4.5]dec-6-yl)-ethyl]-4-isopropyl-2,3-dimethoxy-phenyl}-methanol 
• 176901-52-3 6-[2-(3-Isopropyl-4,5-dimethoxy-phenyl)-ethyl]-7,7-dimethyl-1,4-dioxa-spiro[4.5]decane 
• 176901-51-2 2-[2-(3-isopropyl-4,5-dimethoxyphenyl)ethyl]-5,5-dimethyl-cyclohexan-1-one 
• 181016-82-0 5-[2-(3-isopropyl-4,5-dimethoxyphenyl)ethyl]-5,5-dimethyl-2-cyclohexen-1-one 
• 181016-81-9 5-(2-Iodo-ethyl)-1-isopropyl-2,3-dimethoxy-benzene 
• 181016-79-5 2-(3-isopropenyl-4,5-dimethoxyphenyl)ethanol 
• 181016-80-8 2-(3-isopropyl-4,5-dimethoxyphenyl)ethanol 
• 850254-57-8 5-[2-(3-isopropyl-4,5-dimethoxy-phenyl)-2-methoxycarbonyloxy-ethyl]-4,4,5-trimethyl-2-oxo-cyclohexanecarboxylic acid methyl ester 
• 850254-52-3 3-[2-(3-isopropyl-4,5-dimethoxy-phenyl)-2-methoxycarbonyloxy-ethyl]-3,4,4-trimethyl-6-oxo-cyclohex-1-enecarboxylic acid methyl ester 
• 850254-59-0 3-[(E)-2-(3-Isopropyl-4,5-dimethoxy-phenyl)-vinyl]-3,4,4-trimethyl-6-oxo-cyclohex-1-enecarboxylic acid methyl ester 
• 850254-56-7 4-[2-hydroxy-2-(3-isopropyl-4,5-dimethoxy-phenyl)-ethyl]-3,3,4-trimethyl-cyclohexanone 
• 850254-61-4 4-[(E)-2-(3-Isopropyl-4,5-dimethoxy-phenyl)-vinyl]-3,3,4-trimethyl-cyclohexanone 
• 850254-51-2 5‐bromo‐1‐isopropyl‐2,3‐dimethoxybenzene 

Relevant academic research and scientific papers

Synthesis of [6,6,m]-Tricyclic Compounds via [4+2] Cycloaddition with Au or Cu Catalyst

We synthesized [6,6,6]- and [6,6,7]-tricyclic compounds via intramolecular [4+2] cycloaddition by gold or copper catalysts. Substrates for cyclization were prepared by coupling reactions between eight types of diyne and four types of aromatic moieties. We have successfully synthesized eleven tricyclic compounds.

Total Synthesis of 1-Oxomiltirone and Arucadiol

A practical and efficient approach for the total synthesis of arucadiol and 1-oxomiltirone is reported. The key step which involves an intramolecular [4+2] cycloaddition catalyzed by gold(III) bromide or copper(II) triflate leads to the formation of 6-6-6-fused aromatic abietane core.

The total synthesis of pygmaeocin C

Making use of a recently developed intramolecular Friedel-Crafts alkylation process as the key operation, the first total synthesis, in racemic form, of pygmaeocin C has been achieved. Georg Thieme Verlag Stuttgart.

The first total synthesis of (±)-demethyl salvicanol

Demethyl salvicanol, a novel rearranged 9(10 → 20)-abeo-8, 11, 13-triene diterpene, has been synthesized for the first time. The zinc-promoted coupling reaction of benzyl bromide with ketone and the alkylation of ketone with iodide are the key steps.