176961-13-0Relevant articles and documents
Novel method for cheaply and efficiently synthesizing 2-dihydroxyboro-N-dimethylisooxazolyl-N-methoxyethoxymethyl benzsulfamide
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, (2017/04/12)
The invention relates to a novel method for cheaply and efficiently synthesizing 2-dihydroxyboro-N-dimethylisooxazolyl-N-methoxyethoxymethyl benzsulfamide. The full name of the 2-dihydroxyboro-N-dimethylisooxazolyl-N-methoxyethoxymethyl benzsulfamide is 2
Discovery of 4'-[(imidazol-1-yl)methyl]biphenyl-2-sulfonamides as dual endothelin/angiotensin II receptor antagonists.
Tellew, John E,Baska, Rose Ann F,Beyer, Sophie M,Carlson, Kenneth E,Cornelius, Lyndon A,Fadnis, Leena,Gu, Zhengxiang,Kunst, Bridgette L,Kowala, Mark C,Monshizadegan, Hossain,Murugesan, Natesan,Ryan, Carol S,Valentine, Maria T,Yang, Yifan,Macor, John E
, p. 1093 - 1096 (2007/10/03)
A series of 4'-[(imidazol-1-yl)methyl]biphenylsulfonamides has potent antagonist activity against both angiotensin II AT(1) and endothelin ET(A) receptors. Such dual-acting antagonists could have utility in the treatment of hypertension, heart failure, an
HETEROARYL SUBSTITUTED PHENYL ISOXAZOLE SULFONAMIDE ENDOTHELIN ANTAGONISTS
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, (2008/06/13)
Compounds of the formula STR1 inhibit the activity of endothelin.