176970-05-1

Basic information

• Product Name: (S)-2-Benzyloxycarbonylamino-1,4-bis(methanesulf
• Synonyms: (S)-2-Benzyloxycarbonylamino-1,4-bis(methanesulf;Carbamicacid,[(1S)-3-[(methylsulfonyl)oxy]-1-[[(methylsulfonyl)oxy]methyl]propyl]-,phenylmethylester(9CI);Carbamicacid,[3-[(methylsulfonyl)oxy]-1-[[(methylsulfonyl)oxy]methyl]propyl]-,phenylmethylester,(S)-;(S)-2-Benzyloxycarbonylamino-1,4-bis(methanesulfonyloxy)butane;[(1S)-3-[(Methylsulfonyl)oxy]-1-[[(methylsulfonyl)oxy]methyl]propyl]carbamic acid phenylmethyl ester
• CAS NO: 176970-05-1
• Molecular Formula: C₁₄H₂₁NO₈S₂
• Molecular Weight: 395.44844
• Mol File: 176970-05-1.mol

Chemical Properties

• Boiling Point: 656.961 °C at 760 mmHg
• Flash Point: 351.118 °C
• Appearance: /
• Density: 1.369
• PKA: 11.06±0.46(Predicted)
• CAS DataBase Reference: (S)-2-Benzyloxycarbonylamino-1,4-bis(methanesulf(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-Benzyloxycarbonylamino-1,4-bis(methanesulf(176970-05-1)
• EPA Substance Registry System: (S)-2-Benzyloxycarbonylamino-1,4-bis(methanesulf(176970-05-1)

Safety Data

• Hazardous Substances Data: 176970-05-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
(S)-2-Benzyloxycarbonylamino-1,4-bis(methanesulf is used as a key intermediate in organic synthesis for the creation of intricate molecular structures. Its unique structure allows for versatile reactions and the formation of a wide range of compounds.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (S)-2-Benzyloxycarbonylamino-1,4-bis(methanesulf is employed as a reagent in peptide synthesis. Peptides are crucial in the development of new drugs and in understanding various biological processes, making this compound an essential tool for researchers in drug development.
Used in Drug Development:
(S)-2-Benzyloxycarbonylamino-1,4-bis(methanesulf's structure and properties make it a valuable molecule for chemists and researchers working in the fields of organic chemistry and drug development. Its role in the synthesis of peptides contributes to the advancement of medicinal chemistry and the discovery of novel therapeutic agents.

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 118219-23-1 [(1S)-3-hydroxy-1-(hydroxymethyl)propyl]carbamic acid phenylmethyl ester 
• 35909-93-4 dimethyl (2S)-2-[(phenylmethoxy)carbonylamino]-butane-1,4-dioate 
• 1152-61-0 N-Cbz-L-Asp 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 176970-10-8 (S)-1-allyl-3-(benzyloxycarbonylamino)pyrrolidine 
• 474542-94-4 N-propyl-3-(benzyloxycarbonylamino)pyrrolidine 
• 176970-12-0 (S)-benzyl pyrrolidin-3-ylcarbamate 

Relevant articles and documents

Economical synthesis of tert-butyl (S)-3-aminopyrrolidine-1-carboxylate from L-aspartic acid

3-Aminopyrrolidine building block was used as the intermediate for many pharmaceutically active substances. Starting from L-aspartic acid, optically active (S)-tert-butyl-3-aminopyrrolidine-1-carboxylate was synthesized, and the reaction conditions were optimized in each step. The procedure of each step was discussed in detail and could be useful for the industrial preparation. This process was featured by readily available starting material, mild reaction conditions, easy work-up, and economy.

Practical synthesis of (S)-3-(p-nitrobenzyloxy-carbonylamino)pyrrolidine and its related compounds from L-aspartic acid

An efficient method for the preparation of (S)-3-aminopyrrolidine derivatives was developed starting from L-aspartic acid, which involves an efficient formation of a pyrrolidine-ring from allylamine and a practical Pd/C-catalyzed cleavage of N-allyl prote