176970-12-0 Usage
Uses
Used in Pharmaceutical Research:
(S)-3-N-CBZ-AMINOPYRROLIDINE is used as a chiral amine in pharmaceutical research for the development of enantiomerically pure drug molecules. Its specific spatial arrangement of atoms allows for the creation of drugs with targeted effects, reducing potential side effects and improving therapeutic outcomes.
Used in Drug Synthesis:
(S)-3-N-CBZ-AMINOPYRROLIDINE is used as a key intermediate in the synthesis of various pharmaceuticals and chemicals. Its carbobenzyloxy (CBZ) protecting group plays a crucial role in the synthesis process, ensuring the selective protection of the amino group during chemical reactions. This allows for the controlled formation of complex organic molecules with desired properties.
Used in the Development of New Drugs:
(S)-3-N-CBZ-AMINOPYRROLIDINE is utilized in the development of new drugs, particularly in the synthesis of chiral compounds. Its unique structure and properties enable the creation of novel drug candidates with improved efficacy, selectivity, and safety profiles. (S)-3-N-CBZ-AMINOPYRROLIDINE serves as a valuable building block in the design and synthesis of innovative pharmaceutical agents.
Check Digit Verification of cas no
The CAS Registry Mumber 176970-12-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,6,9,7 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 176970-12:
(8*1)+(7*7)+(6*6)+(5*9)+(4*7)+(3*0)+(2*1)+(1*2)=170
170 % 10 = 0
So 176970-12-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H16N2O2/c15-12(14-11-6-7-13-8-11)16-9-10-4-2-1-3-5-10/h1-5,11,13H,6-9H2,(H,14,15)/t11-/m0/s1
176970-12-0Relevant articles and documents
Economical synthesis of tert-butyl (S)-3-aminopyrrolidine-1-carboxylate from L-aspartic acid
Han, Zhi-Jian,Li, Yang-Bing,Gu, Bao-Hong,Li, Yu-Min,Chen, Hao
supporting information, p. 2452 - 2456 (2018/10/20)
3-Aminopyrrolidine building block was used as the intermediate for many pharmaceutically active substances. Starting from L-aspartic acid, optically active (S)-tert-butyl-3-aminopyrrolidine-1-carboxylate was synthesized, and the reaction conditions were optimized in each step. The procedure of each step was discussed in detail and could be useful for the industrial preparation. This process was featured by readily available starting material, mild reaction conditions, easy work-up, and economy.
Practical synthesis of (S)-3-(p-nitrobenzyloxy-carbonylamino)pyrrolidine and its related compounds from L-aspartic acid
Tomori, Hiroshi,Shibutani, Kuniko,Ogura, Katsuyuki
, p. 213 - 225 (2007/10/03)
An efficient method for the preparation of (S)-3-aminopyrrolidine derivatives was developed starting from L-aspartic acid, which involves an efficient formation of a pyrrolidine-ring from allylamine and a practical Pd/C-catalyzed cleavage of N-allyl prote