17714-57-7Relevant academic research and scientific papers
Nickel-Catalyzed Ring Expansion of Cyclobutanones towards Indanones
Chen, Tengyun,Wu, Yunkai,Han, Peilin,Gao, Jiqiang,Wu, Yuanqi,Zhao, Jinbo,Liang, Haotian,Liu, Yongsheng,Liu, Yu
, (2022/01/13)
Despite recent advances in catalytic ring-opening/cross-coupling process of o-halogen tethered phenylcyclobutanones with other partners, single-component ring expansion of such precursors towards 3-methylindanones has not been disclosed. We present herein a nickel catalyzed C?C bond reconstruction sequence of o-bromophenylcyclobutanones using H2O as hydrogen donor, leading to a series of indanones, which can be further converted into other benzene-fused cyclic compounds.
Preparation method of indanone compound
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Paragraph 0035-0044; 0052-0081, (2021/08/07)
The invention provides a preparation method of a hydrindone compound, and belongs to the technical field of compound synthesis. The method comprises the following steps: under the action of a nickel catalyst, a ligand, bis(pinacolato)diboron, alkali and water, reacting o-bromophenyl cyclobutanone of a formula 1 structure in a solvent at 70-90 DEG C for 12-24 hours, and separating and purifying a product after the reaction is finished to obtain the indanone compound of the formula I structure. The method is simple, raw materials are easy to obtain, experimental operation is simple and convenient, and the yield of the prepared product is moderate.
Asymmetric Induction in Hydroacylation by Cooperative Iminium Ion-Transition-Metal Catalysis
Rastelli, Ettore J.,Truong, Ngoc T.,Coltart, Don M.
, p. 5588 - 5591 (2016/11/17)
A new strategy for the rhodium-catalyzed enantioselective hydroacylation is described. This has been achieved through the merger of iminium ion catalysis and transition-metal catalysis such that asymmetric induction derives from a readily accessible, inexpensive chiral nonracemic secondary amine catalyst rather than a chiral nonracemic phosphine as is typical of conventional asymmetric hydroacylation methods.
Microwave-assisted one-pot synthesis of 1-indanones from arenes and α,β-unsaturated acyl chlorides
Yin, Wei,Ma, Yuan,Xu, Jiaxi,Zhao, Yufen
, p. 4312 - 4315 (2007/10/03)
A series of 1-indanones were synthesized in good yields via tandem Friedel-Crafts acylation and Nazarov cyclization of arenes and α,β-unsaturated acyl chlorides in the presence of aluminum chloride under microwave irradiation.
