1772-77-6

Upstream product

• 67-56-1 methanol 
• 1772-65-2 (E)-4-(3-nitrophenyl)-2-oxo-3-butenoic acid 

Downstream Products

• 1228393-41-6 trimethyl 2-(3-nitrophenyl)-4-oxobutane-1,1,4-tricarboxylate 
• 1257520-14-1 (4R,4aS,7aS)-methyl 4-(3-nitrophenyl)-4,4a,5,7a-tetrahydrocyclopenta[b]pyran-2-carboxylate 
• 1375648-56-8 methyl 4-(3-nitrophenyl)-2-oxo-4-(1H-pyrazol-1-yl)butanoate 
• 1398245-06-1 (+)-4-(1H-pyrrol-2-yl)-2-oxo-4-(3-nitrophenyl)butyric acid methyl ester 
• 1350721-95-7 (R,Z)-1-(methoxycarbonyl)-4-nitro-3-(3-nitrophenyl)but-1-enyl benzoate 
• 1350722-35-8 (R,Z)-ethyl 2-(butyryloxy)-5-nitro-4-(3-nitrophenyl)pent-2-enoate 
• 148214-97-5 ethyl 2-bromoacetylamino-6-methyl-4-(3-nitrophenyl)-5-pyridinecarboxylate 
• 148214-95-3 ethyl 2-methoxycarbonyl-6-methyl-4-(3-nitrophenyl)-5-pyridinecarboxylate 
• 132391-36-7 5-ethoxycarbonyl-6-methyl-4-(3-nitrophenyl)-2-pyridinecarboxylic acid 
• 148214-96-4 ethyl 6-amino-2-methyl-4-(3-nitrophenyl)-3-pyridinecarboxylate 
• 148214-94-2 ethyl 1,4-dihydro-2-methoxycarbonyl-6-methyl-4-(3-nitrophenyl)-5-pyridinecarboxylate 

Relevant academic research and scientific papers

Deracemisation of aryl substituted α-hydroxy esters using Candida parapsilosis ATCC 7330: Effect of substrate structure and mechanism

Candida parapsilosis ATCC 7330 was found to be an efficient biocatalyst for the deracemisation of aryl α-hydroxy esters (65-85% yield and 90-99% ee). A variety of aryl and aryl substituted α-hydroxy esters were synthesized to reflect steric and electronic effects on biocatalytic deracemisation. The mechanism of this biocatalytic deracemisation was found to be stereoinversion.