17724-16-2

Upstream product

• 95-88-5 4-Chlororesorcinol 
• 103068-41-3 4-fluororesorcinol 
• 106120-04-1 5-bromoresorcinol 
• 108-73-6 3,5-dihydroxyphenol 
• 617-99-2 benzene 1,3,5-trisulfonic acid 

Downstream Products

• 605655-07-0 dihydroxy benzene sulfonyl chloride 
• 605653-16-5 C₁₆H₂₁ClO₆S 

Relevant academic research and scientific papers

Reductive dehalogenation and dehalogenative sulfonation of phenols and heteroaromatics with sodium sulfite in an aqueous medium

Prototropic tautomerism was used as a tool for the reductive dehalogenation of (hetero)aryl bromides and iodides, or dehalogenative sulfonation of (hetero)aryl chlorides and fluorides, using sodium sulfite as the sole reagent in an aqueous medium. This protocol does not require a metal or phase transfer catalyst and avoids using organic solvent as the reaction medium. This method is especially suitable for substrates that readily tautomerize (such as 2-or 4-halogenated aminophenols and 4-halogenated resorcinols), for which dehalogenation or sulfonation proceeds under mild reaction conditions (≤60 °C). As sodium sulfite is an inexpensive, safe, and environmentally less hazardous reagent, this method has at least three potential applications: (i) in the deprotection of halogens as protecting groups, using sodium sulfite as a reducing agent; (ii) in the sulfonation of aromatic halides under mild reaction conditions avoiding hazardous and corrosive reagents/solvents; and (iii) in the transformation of toxic halogenated aromatics into less harmful compounds.

Anionic Head Containing Oxacalix[2]arene[2]triazines: Synthesis and Anion- Directed Self-Assembly in Solution and Solid State

A series of oxacalix[2]arene[2]triazines bearing one anionic head such as carboxylate, sulfonate, sulfate, and phosphate were synthesized. With the anionic head and complementary V-shape electron-deficient cavity, these macrocycles can serve as dual building units, and their anion directed self-assembly was investigated. The formation of oligomeric aggregates in solution was revealed by nuclear magnetic resonance, dynamic light scattering, and mass spectroscopy. Crystal structures further confirmed chainlike assembly formation directed by anion- interactions.

METHOD AND COMPOSITIONS FOR TREATING HIV INFECTIONS

Described herein are compounds and compositions that are useful in the treatment of HIV, AIDS, and AIDS-related diseases. In addition, compounds are described herein that are capable of inhibiting the dimerization of HIV proteases.