177499-65-9Relevant academic research and scientific papers
Selective A1-adenosine receptor antagonists identified using yeast Saccharomyces cerevisiae functional assays.
Campbell,Cartwright,Chen,Chen,Duzic,Fu,Loveland,Manning,McKibben,Pleiman,Silverman,Trueheart,Webb,Wilkinson,Witter,Xie,Castelhano
, p. 2413 - 2418 (2007/10/03)
Evaluation of a biased "library" of pyrrolo[2,3-d]pyrimidines using yeast-based functional assays expressing human A1- and A2a-adenosine receptors, led to the A1 selective antagonist 4b. A direct correlation between yeast functional activity and binding d
