251946-72-2

Upstream product

• 98-88-4 benzoyl chloride 
• 104915-38-0 2-Amino-4,5-dimethyl-(1-(DL-1-phenylethyl)-3-pyrrolcarbonitril) 

Downstream Products

• 177499-66-0 4-Chloro-5,6-dimethyl-2-phenyl-7H-pyrrolo[2,3-d]pyrimidine 
• 177499-64-8 5,6-Dimethyl-2-phenyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one 
• 177499-65-9 5,6-dimethyl-2-phenyl-7-(1-phenyl-ethyl)-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one 

Relevant academic research and scientific papers

Selective A1-adenosine receptor antagonists identified using yeast Saccharomyces cerevisiae functional assays.

Evaluation of a biased "library" of pyrrolo[2,3-d]pyrimidines using yeast-based functional assays expressing human A1- and A2a-adenosine receptors, led to the A1 selective antagonist 4b. A direct correlation between yeast functional activity and binding d

Compounds specific to adenosine A1 receptors and uses thereof

This invention pertains to compounds which specifically inhibit the adenosine A1 receptor and the use of these compounds to treat a disease associated with A1 adenosine receptors in a subject.