177530-95-9Relevant academic research and scientific papers
Asymmetric autocatalysis enables an improved synthesis of efavirenz
Chinkov, Nicka,Warm, Aleksander,Carreira, Erick M.
, p. 2957 - 2961 (2011)
(Chemical Equation Presented) Priming the pump: An asymmetric autocatalytic zinc acetylide addition employs catalytic amounts of the enantiomerically pure product as part of a chiral cocktail. This new strategy enables an improved synthesis of a key precursor to efavirenz (see scheme).
