177602-10-7

Basic information

• Product Name: C₁₄H₁₃NO₂
• Synonyms: C₁₄H₁₃NO₂
• CAS NO: 177602-10-7
• Molecular Weight: 227.263
• Mol File: 177602-10-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₃NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₃NO₂(177602-10-7)
• EPA Substance Registry System: C₁₄H₁₃NO₂(177602-10-7)

Safety Data

• Hazardous Substances Data: 177602-10-7(Hazardous Substances Data)

Upstream product

• 108-22-5 Isopropenyl acetate 
• 31796-72-2 phenyl(2-pyridinyl)methanol 
• 119718-88-6 O-acetyl (S)-mandelonitrile 
• 74-86-2 acetylene 

Relevant articles and documents

Kinetic resolution of diarylmethanols using a mutated variant of lipase CALB

An enzymatic kinetic resolution of diarylmethanols via acylation has been developed. This was achieved by the use of a mutated variant of CALB that accepts larger substrates compared to the wild type. By the use of diarylmethanols with two differently sized aryl groups, enantioselective transformations were achieved. A larger size-difference led to a higher enantioselectivity. In addition, substrates with electronically different aryl groups, such as phenyl and pyridyl, also gave an enantioselective reaction. The highest E value was observed with a substrate where steric and electronic effects were combined.