177932-58-0

Basic information

• Product Name: (3aS,4S,6R,7aR)-2-Benzyl-4-(2-methoxy-phenyl)-6-methyl-octahydro-isoindol-4-ol
• Synonyms: (3aS,4S,6R,7aR)-2-Benzyl-4-(2-methoxy-phenyl)-6-methyl-octahydro-isoindol-4-ol
• CAS NO: 177932-58-0
• Molecular Weight: 351.489
• Mol File: 177932-58-0.mol

Chemical Properties

• CAS DataBase Reference: (3aS,4S,6R,7aR)-2-Benzyl-4-(2-methoxy-phenyl)-6-methyl-octahydro-isoindol-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (3aS,4S,6R,7aR)-2-Benzyl-4-(2-methoxy-phenyl)-6-methyl-octahydro-isoindol-4-ol(177932-58-0)
• EPA Substance Registry System: (3aS,4S,6R,7aR)-2-Benzyl-4-(2-methoxy-phenyl)-6-methyl-octahydro-isoindol-4-ol(177932-58-0)

Safety Data

• Hazardous Substances Data: 177932-58-0(Hazardous Substances Data)

Upstream product

• 177932-57-9 (3aS,6R,7aR)-2-Benzyl-6-methyl-octahydro-isoindol-4-one 
• 31600-86-9 2-methoxyphenyllithium 
• 289041-22-1 Imidazole-1-carbothioic acid O-((3aR,4S,5S,7aS)-2-benzyl-5-methyl-7-oxo-octahydro-isoindol-4-yl) ester 
• 289041-20-9 (3aS,4S,7S,7aR)-2-Benzyl-4-hydroxymethyl-2,3,3a,4,7,7a-hexahydro-1H-isoindole-4,7-diol 
• 289041-21-0 (3aS,6S,7S,7aR)-2-Benzyl-7-hydroxy-6-methyl-octahydro-isoindol-4-one 
• 1631-26-1 1-benzyl-1H-pyrrole-2,5-dione 
• 54307-74-3 (R)-5-methyl-cyclohex-2-enone 
• 93102-06-8 N-benzyl-N-(butyloxymethyl)trimethylsilylmethylamine 

Relevant articles and documents

Asymmetric synthesis of the key intermediate of an SP antagonist RPR107880 using a base-catalyzed Diels-Alder reaction

An asymmetric synthesis of the key intermediate of RPR 107880, a substance P antagonist, using a base-catalyzed Diels-Alder reaction of 3- hydroxy-2-pyrone and N-benzylmaleimide is described. (C) 2000 Elsevier Science Ltd.

Enantiospecific synthesis of rpr 107880 : A new non peptide substance P antagonist

The synthesis of enantiomerically pure RPR 107880 is described. The synthetic strategy is based on the use of the readily available and inexpensive (R)-(+)-pulegone. Copyright