177949-92-7 Usage
General Description
(E)-4,4,5,5-tetramethyl-2-(3-methylbut-1-en-1-yl)-1,3,2-dioxaborolane, also known as TMEDA, is a chemical compound commonly used as a ligand in organic synthesis and catalysis. It is a colorless liquid with a molecular formula C11H21BO2 and a molecular weight of 200.1 g/mol. TMEDA is a versatile chelating agent that forms stable complexes with a wide range of metal ions, particularly those of transition metals. Its chelating ability and steric bulk make it useful in coordinating metal atoms in catalytic processes, such as polymerization and cross-coupling reactions. TMEDA is also known for its role in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and fine chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 177949-92-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,7,9,4 and 9 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 177949-92:
(8*1)+(7*7)+(6*7)+(5*9)+(4*4)+(3*9)+(2*9)+(1*2)=207
207 % 10 = 7
So 177949-92-7 is a valid CAS Registry Number.
177949-92-7Relevant articles and documents
A Catalytic Dual Isomerization/Allylboration Sequence for the Stereoselective Construction of Congested Secondary Homoallylic Alcohols
Liu, Yangbin,Mazet, Clément
, p. 5638 - 5650 (2020/05/19)
A catalytic sequence for the diastereo- and enantioselective preparation of homoallylic alcohols with an adjacent quaternary (stereo)center is reported. The one-pot process relies on the use of a single (achiral or chiral) iridium complex to catalyze the concomitant isomerization of primary allylic alcohols and homoallylboronates into (chiral) aldehydes and allylboronates, respectively. In the same flask, a chiral Br?nsted acid is added next to engage the isomerization products into a stereocontrolled allylboration reaction. Structural variations have been performed on both the allylic alcohols and the homoallylboronates. This mild process affords an array of stereochemically congested and complex chiral secondary homoallylic alcohols in high yield, excellent diastereoselectivity, and usually high enantioselectivity.
