1780-33-2

Usage

Uses

Used in Pharmaceutical Industry:
4,6-Dichloro-2,5-Dimethyl Pyrimidine is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of complex organic molecules that can be utilized in medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 4,6-Dichloro-2,5-Dimethyl Pyrimidine is used as a precursor in the production of fungicides, herbicides, and insecticides, due to its potential to form active ingredients that combat various agricultural pests and diseases.
Used in Chemical Industry:
4,6-Dichloro-2,5-Dimethyl Pyrimidine is employed as a versatile intermediate for the synthesis of a wide range of organic compounds in the chemical industry, highlighting its importance in creating new chemical entities for various applications.

InChI:InChI=1/C6H6Cl2N2/c1-3-5(7)9-4(2)10-6(3)8/h1-2H3

Upstream product

• 857412-07-8 2,5-dimethyl-1H-pyrimidine-4,6-dione 
• 1194-74-7 4,6-Dihydroxy-2,5-dimethylpyrimidin 

Downstream Products

• 874494-76-5 (6-chloro-2,5-dimethyl-pyrimidin-4-yl)-(4-chloro-phenyl)-amine 
• 22868-76-4 2,5-dimethylpyrimidine 
• 1194-73-6 6-chloro-2,5-dimethyl-3H-pyrimidin-4-one 
• 18260-92-9 6-chloro-2,5-dimethyl-pyrimidin-4-ylamine 
• 13265-42-4 2,5-dimethyl-pyrimidine-4,6-diyldiamine 
• 1780-34-3 5-bromomethyl-4,6-dichloro-2-methyl-pyrimidine 
• 184241-38-1 (6-Chloro-2,5-dimethyl-pyrimidin-4-yl)-(2,4,6-trichloro-phenyl)-amine 
• 175140-34-8 4-chloro-6-(mesityloxy)-2,5-dimethylpyrimidine 
• 184241-41-6 N-Cyclopropylmethyl-2,5-dimethyl-N-propyl-N'-(2,4,6-trichloro-phenyl)-pyrimidine-4,6-diamine 
• 73-70-1 2,5-dimethyl-pyrimidin-4-ylamine 
• 14278-61-6 6-amino-2,5-dimethyl-3H-pyrimidin-4-one 
• 41077-58-1 5-methoxymethyl-2-methyl-3H-pyrimidin-4-one 
• 5423-97-2 5-ethoxymethyl-2-methyl-3H-pyrimidin-4-one 
• 100882-19-7 benzaldehyde-(6-methoxy-2,5-dimethyl-pyrimidin-4-ylhydrazone) 

Relevant academic research and scientific papers

HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF

Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes

Pyrimidine Derivatives Which Are Antagonists Of Vitronectin Receptor

A subject of the invention is the compounds of formula (I); in which R1, R2, R3, R4 and R have the meanings indicated in the description, their preparation process, their use as medicaments having an antagonist activity on the vitronectin receptor and the pharmaceutical compositions containing them.

Novel vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same

A subject of the invention is the compounds of formula (I): in which R1, R2, R3, R4 and G have the meanings indicated in the description, their preparation process, their use as medicaments having an antagonist activity on the vitronectin receptor and the pharmaceutical compositions containing them.

PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF

The present invention encompasses novel substituted pyrimidine compounds of Formula (I): which act as MCH receptor antagonists. These compounds are useful in pharmaceutical compositions whose use includes prophylaxis or treatment of improving memory function, sleeping and arousal, anxiety, depression, mood disorders, seizure, obesity, diabetes, appetite and eating disorders, cardiovascular disease, hypertension, dyslipidemia, myocardial infarction, binge eating disorders including bulimia, anorexia, mental disorders including manic depression, schizophrenia, delirium, dementia, stress, cognitive disorders, attention deficit disorder, substance abuse disorders and dyskinesias including Parkinson’s disease, epilepsy, and addiction.

5-substituted-6-aminopyrimidines, composition and uses as cardiotonic agents for increasing cardiac contractility

Herein is disclosed amino-pyrimidine derivatives, therapeutically acceptable acid addition salts thereof, processes for their preparation, methods of using the derivatives and pharmaceutical compositions. The derivatives are useful for increasing cardiac contractility in a mammal.