178240-01-2Relevant academic research and scientific papers
Process for the preparation of phenyl glyoxylic acid ester oximes
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Page column 4, (2010/02/06)
The invention relates to a process for the preparation of compounds of formula (I) wherein: R1is optionally substituted alkyl, R2is C1-C6alkyl, C3-C6cycloalkyl, C3-C6cycloalkyl-C1-C2alkyl, aryl, aryl-C1-C2alkyl, heterocyclyl, heterocycly-C1-C2alkyl, which groups are optionally substituted by alkyl, alkoxy, or halogen; in which process (I) an aniline of formula (II), is diazotized with an organic or inorganic nitrite or nitrous acid; (2) the resulting diazonium salt is reacted with an oxime of formula (III) in presence of a copper(II)-salt.
