120974-97-2

Basic information

• Product Name: Methyl 2-(MethoxyiMino)-2-o-tolylacetate
• Synonyms: Methyl 2-(MethoxyiMino)-2-o-tolylacetate;(E)-alpha-(Methoxyimino)-2-methylbenzeneacetic acid methyl ester;Methyl (E)-2-MethoxyiMino-[2-(o-Methyl)phenyl] acetate;Benzeneacetic acid, a-(MethoxyiMino)-2-Methyl-, Methyl ester, (E)-;(E)-2-methoxyimino-[(2-O-methyl) phenyl] acetate;(E)-methyl 2-(methoxyimino)-2-o-tolylacetate
• CAS NO: 120974-97-2
• Molecular Formula: C₁₁H₁₃NO₃
• Molecular Weight: 207.22582
• EINECS: 1533716-785-6
• Mol File: 120974-97-2.mol
• Article Data: 17

Chemical Properties

• Melting Point: 66-68℃
• Boiling Point: 282℃
• Flash Point: 117℃
• Appearance: /
• Density: 1.07
• Storage Temp.: 2-8°C
• Solubility: Dichloromethane (Slightly), Chloroform (Slightly), Ethyl Acetate (Slightly)
• CAS DataBase Reference: Methyl 2-(MethoxyiMino)-2-o-tolylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-(MethoxyiMino)-2-o-tolylacetate(120974-97-2)
• EPA Substance Registry System: Methyl 2-(MethoxyiMino)-2-o-tolylacetate(120974-97-2)

Safety Data

• Hazardous Substances Data: 120974-97-2(Hazardous Substances Data)

Usage

Physical Form

Solid

Uses

(E)-α-(Methoxyimino)-2-methylbenzeneacetic Acid Methyl Ester is an intermediate in the synthesis of Trifloxystrobin (T778900), a broad-spectrum foliar fungicide used in plant protection.

Upstream product

• 34966-54-6 methyl 2-oxo-2-(o-tolyl)acetate 
• 593-56-6 N-methoxylamine hydrochloride 
• 77-78-1 dimethyl sulfate 
• 74-87-3 methylene chloride 
• 115199-21-8 methyl 2-methyl-α-methoxyiminophenylacetate 
• 1462379-43-6 (E)-2-methoxyimino-2-(o-tolyl)acetic acid 
• 144106-03-6 (Z)-2-(2-tolyl)-2-methoxyiminoacetic acid methyl ester 
• 74-88-4 methyl iodide 
• 22364-68-7 2-tolylmethylnitrile 
• 178983-50-1 2-methyl-a-cyanobenzoxime potassium 
• 107960-33-8 2-methyl-α-hydroxyiminobenzeneacetonitrile 
• 67-56-1 methanol 
• 95-53-4 o-toluidine 
• 95-46-5 2-methylphenyl bromide 

Downstream Products

• 133409-72-0 methyl (E)-2-[2-(bromomethyl)phenyl]-2-(methoxyimino)acetate 
• 43121-43-3 trifloxystrobin 

Relevant articles and documents

Synthesis and fungicidal activity of (E)-α-(Methoxyimino)benzeneacetate derivatives containing 1,2,4-triazole schiff base side Chain

Figure presented To find new strobilurin analogs with high activity against resistant pathogens, twelve (E)-α-(methoxyimino)benzeneacetate derivatives containing 1,2,4-triazole Schiff base side chain 3a-3l were designed and synthesized. Their structures were confirmed by IR, 1H-NMR, EIMS, and elemental analyses. Bioassays indicated that most of the target compounds showed moderate to good fungicidal activities against Physalospora piricola Nose and Alternaria solani. For example, compounds 3d, 3e, and 3f possessed 99.5%, 100%, and 95.6% inhibition against Physalospora piricola Nose, whereas compounds 3d, 3f, and 3g exhibited 92%, 91%, and 92% inhibition against Alternaria solani at the concentration of 50 mg/L, respectively.

Intermediate for preparing trifloxystrobin and synthesis method of intermediate

The invention relates to an intermediate for preparing trifloxystrobin and a synthesis method of the intermediate, wherein the synthesis method comprises the steps: by taking 2-oxime-o-methyl phenylacetonitrile as a raw material, heating and hydrolyzing i

Green synthetic method of kresoxim-methyl

The invention belongs to the technical field of fine chemical engineering, and particularly relates to a green synthetic method of kresoxim-methyl. The method comprises the following steps: carrying out nitrous nitrification by using 2-methylbenzyl cyanide as an initial raw material, carrying out methylation, carrying out hydrolytic methylation or hydrolytic esterification, carrying out bromination and carrying out an etherification reaction to obtain the high-content kresoxim-methyl. The method provided by the invention has a short reaction period, a high conversion rate, and excellent product quality, changes the defect that high-concentration hydrochloric acid gas is used for preparation in a traditional process, and has the advantages of simple operation steps, simple equipment, low energy consumption, a short period, high productivity and environmental protection.