133409-72-0

Basic information

• Product Name: (E)-Methyl-2-(2-broMoMethylphenyl)-2-MethoxyiMinoacetate
• Synonyms: (E)-Methyl-2-(2-broMoMethylphenyl)-2-MethoxyiMinoacetate;Methyl-2-(2-broMoMethylphenyl)-2-MethoxyiMinoacetate;Benzeneacetic acid, 2-(broMoMethyl)-a-(MethoxyiMino)-, Methyl ester, (aE)-;(E)-2-bromomethyl-α-methoxyimino phenylacetate;(E)-Methyl 2-(methoxyimino)-2-[2-(bromomethyl)phenyl]acetate;(E)-2-[2-(Bromomethyl)phenyl]-2-(methoxyimino)acetic Acid Methyl Ester;(alphaE)-2-Bromomethyl-alpha-(methoxyimino)phenyl-acetic acid methyl ester
• CAS NO: 133409-72-0
• Molecular Formula: C₁₁H₁₂BrNO₃
• Molecular Weight: 286.12188
• EINECS: -0
• Mol File: 133409-72-0.mol
• Article Data: 22

Chemical Properties

• Melting Point: 45-48 °C
• Boiling Point: 343.7±44.0 °C(Predicted)
• Appearance: /
• Density: 1.38±0.1 g/cm3(Predicted)
• Solubility: DCM, Ethyl Acetate
• CAS DataBase Reference: (E)-Methyl-2-(2-broMoMethylphenyl)-2-MethoxyiMinoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-Methyl-2-(2-broMoMethylphenyl)-2-MethoxyiMinoacetate(133409-72-0)
• EPA Substance Registry System: (E)-Methyl-2-(2-broMoMethylphenyl)-2-MethoxyiMinoacetate(133409-72-0)

Safety Data

• Hazardous Substances Data: 133409-72-0(Hazardous Substances Data)

Usage

Uses

(E)-2-[2-(Bromomethyl)phenyl]-2-(methoxyimino)acetic Acid Methyl Ester is an intermediate in the synthesis of metabolites of the agricultural fungicide Kresoxim-methyl (K659000).

Upstream product

• 120974-97-2 methyl-(E)-2-(2-tolyl)-2-methoxyiminoacetate 
• 178240-01-2 methyl (E)-2-hydroxyimino-2-o-tolylacetate 
• 2028-34-4 o-toluene-diazonium chloride 
• 34241-39-9 azobisisobutyronitrile 
• 94-36-0 dibenzoyl peroxide 
• 144106-03-6 (Z)-2-(2-tolyl)-2-methoxyiminoacetic acid methyl ester 
• 107960-33-8 2-methyl-α-hydroxyiminobenzeneacetonitrile 
• 178983-50-1 2-methyl-a-cyanobenzoxime potassium 
• 22364-68-7 2-tolylmethylnitrile 
• 95-53-4 o-toluidine 
• 85589-34-0 2-hydroxy-2-(2-methylphenyl)acetonitrile 
• 529-20-4 2-methylphenyl aldehyde 
• 932-31-0 ortho-tolylmagnesium bromide 
• 577-16-2 2-Methylacetophenone 

Downstream Products

• 133408-88-5 (E)-N-methyl-2-[2-(3-phenoxyphenoxymethyl)phenyl]-2-methoxyiminoacetamide 
• 158668-57-6 Methyl E-2-methoxyimino-2-[(2-[5-(4-chlorophenyl)isoxazol-3-yl]oxymethyl)phenyl]acetate 
• 1009091-71-7 methyl 2-[3-methyl-(2-fluoro-4-chloro-5-ethylsulfonamidophenyl)-4,5-dihydro-5-oxo-1H-1,2,4-triazol-4-yl]methylenephenyl-2-(E)-methoxyiminoacetate 
• 43121-43-3 trifloxystrobin 
• 1607822-56-9 (E,E)-methyl-2-(2-((((1-(1H-benzo[b]thien-2-yl)ethylidene)amino)oxy)-methyl)phenyl)-2-methoxyiminoacetate 
• 1607822-57-0 (E,E)-methyl-2-(2-((((4-chloro-1-(1H-benzo[b]thien-2-yl)ethylidene)-amino)oxy)methyl)phenyl)-2-methoxyiminoacetate 
• 1607822-58-1 (E,E)-methyl 2-(2-((((5-trifluoromethyl-1-(1H-benzo-[b]thien-2-yl)ethylidene)amino)oxy)methyl)phenyl)-2-methoxyiminoacetate 
• 1607822-59-2 (E,E)-methyl-2-(2-((((6-ethylthio-1-(1H-benzo[b]thien-2-yl)ethylidene)amino)oxy)methyl)phenyl)-2-methoxyiminoacetate 

Relevant articles and documents

Green synthetic method of kresoxim-methyl

The invention belongs to the technical field of fine chemical engineering, and particularly relates to a green synthetic method of kresoxim-methyl. The method comprises the following steps: carrying out nitrous nitrification by using 2-methylbenzyl cyanide as an initial raw material, carrying out methylation, carrying out hydrolytic methylation or hydrolytic esterification, carrying out bromination and carrying out an etherification reaction to obtain the high-content kresoxim-methyl. The method provided by the invention has a short reaction period, a high conversion rate, and excellent product quality, changes the defect that high-concentration hydrochloric acid gas is used for preparation in a traditional process, and has the advantages of simple operation steps, simple equipment, low energy consumption, a short period, high productivity and environmental protection.

Benzpyrole derivative containing dithioacetal unit, preparation method and application thereof

The invention discloses a benzpyrole derivative containing a dithioacetal unit, a preparation method and application thereof. The benzpyrole derivative has the general structural formula (I) (being defined as in the specification), in the formula, R1 is substitution hydrogen or a halogen atom, R2 is a substitution aromatic ring, 1-propyl alcohol, methyl, ethyl, propyl, isopropyl, butyl, isobutyl or dodecyl, and X is a halogen atom and the methyl. The benzpyrole derivative has the good biological activity for plant virus diseases, the preparation process is simple, and the production cost is low.

Design, Synthesis, Antiviral Bioactivity, and Defense Mechanisms of Novel Dithioacetal Derivatives Bearing a Strobilurin Moiety

A series of dithioacetal derivatives bearing a strobilurin moiety were designed and synthesized on the basis of our previous work. The antiviral activities of these compounds against Potato virus Y (PVY), Cucumber mosaic virus (CMV), and Tobacco mosaic virus (TMV) were systematically evaluated. Bioassay results indicated that C14 elicited excellent curative and protective activities against PVY, CMV, and TMV. The former had 50% effective concentrations (EC50) of 125.3, 108.9, and 181.7 μg/mL, respectively, and the latter had 148.4, 113.2, and 214.6 μg/mL, respectively, which were significantly superior to those of lead compound 6f (297.6, 259.6, and 582.4 μg/mL and 281.5, 244.3, and 546.3 μg/mL, respectively), Ningnanmycin (440.5, 549.1, and 373.8 μg/mL and 425.3, 513.3, and 242.7 μg/mL, respectively), Chitosan oligosaccharide (553.4, 582.8, and 513.8 μg/mL and 547.3, 570.6, and 507.9 μg/mL, respectively), and Ribavirin (677.4, 690.3, and 686.5 μg/mL and 652.7, 665.4, and 653.4 μg/mL, respectively). Moreover, defensive enzyme activities and RT-qPCR analysis demonstrated that the antiviral activity was associated with the changes of SOD, CAT, and POD activities in tobacco, which was proved by the related proteins of abscisic acid signaling pathway. This work provided a basis for further design, structural modification, and development of dithioacetal derivatives as new antiviral agents.