178242-93-8

Basic information

• Product Name: 4-AMINO-TETRAHYDROPYRAN-4-ACETIC ACID METHYL ESTER
• Synonyms: 4-AMINO-TETRAHYDROPYRAN-4-ACETIC ACID METHYL ESTER ;methyl 2-(4-aminotetrahydro-2H-pyran-4-yl)acetate;REF DUPL: Methyl DL-2-(tetrahydropyran-4-yl)-beta-glycinate;2H-Pyran-4-acetic acid, 4-aminotetrahydro-, methyl ester
• CAS NO: 178242-93-8
• Molecular Formula: C₈H₁₅NO₃
• Molecular Weight: 173.21
• Mol File: 178242-93-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 241°C at 760 mmHg
• Flash Point: 91.5°C
• Appearance: /
• Density: 1.075g/cm³
• Vapor Pressure: 0.0367mmHg at 25°C
• Refractive Index: 1.456
• CAS DataBase Reference: 4-AMINO-TETRAHYDROPYRAN-4-ACETIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-TETRAHYDROPYRAN-4-ACETIC ACID METHYL ESTER(178242-93-8)
• EPA Substance Registry System: 4-AMINO-TETRAHYDROPYRAN-4-ACETIC ACID METHYL ESTER(178242-93-8)

Safety Data

• Hazardous Substances Data: 178242-93-8(Hazardous Substances Data)

Usage

General Description

4-AMINO-TETRAHYDROPYRAN-4-ACETIC ACID METHYL ESTER is a chemical compound with the molecular formula C8H13NO3. It is an ester derivative of 4-amino-tetrahydropyran-4-acetic acid, and is commonly used in organic synthesis and pharmaceutical research. 4-AMINO-TETRAHYDROPYRAN-4-ACETIC ACID METHYL ESTER has potential applications in the development of new drugs and pharmaceuticals due to its structural properties and reactivity. It has also been studied for its potential pharmacological activities in the treatment of various medical conditions. Overall, 4-AMINO-TETRAHYDROPYRAN-4-ACETIC ACID METHYL ESTER is a versatile and important chemical compound with a wide range of potential applications in various fields.

InChI:InChI=1/C8H15NO3/c1-11-7(10)6-8(9)2-4-12-5-3-8/h2-6,9H2,1H3

Upstream product

• 36838-71-8 4-methylene-tetrahydro-pyran 
• 29943-42-8 Tetrahydro-4H-pyran-4-one 
• 138302-49-5 methyl 2-(dihydro-2H-pyran-4-(3H)-ylidene)acetate 
• 67-56-1 methanol 

Downstream Products

• 681284-00-4 {4-[4-(2-methyl-quinolin-4-ylmethoxy)-benzoylamino]-tetrahydro-pyran-4-yl}-acetic acid methyl ester 

Relevant articles and documents

PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND

There are provided compounds having a superior PHD2 inhibitory effect that are represented by general formula (I'): (in the above-mentioned general formula (I'), W, Y, R2, R3, R4, and Y4 are as described hereinabove), or pharmaceutically acceptable salts thereof.

Novel 5-hydroxytryptamine 4 (5-HT4) receptor agonists. Synthesis and gastroprokinetic activity of 4-amino-N-[2-(1-aminocycloalkan-1-yl)ethyl]-5- chloro-2-methoxybenzamides

A novel series of 4-amino-N-[2-(1-aminocycloalkan-1-yl)ethyl]-5-chloro- 2-methoxybenzamide derivatives (1), which had amines conformationally restricted due to the effect of repulsion by neighboring substituents, were prepared and evaluated for 5-hydroxytryptamine 4 (5-HT4) agonistic activities by using the contraction of longitudinal muscle myenteric plexus (LMMP) of guinea pig ileum. One of the most potent compounds in this series was 4-amino-5-chloro-N-[2-(1-dimethylamino-1-cyclohexyl)ethyl]-2- methoxybenzamide (1c, YM-47813) with an EC50 value of 1.0 μM on LMMP. This compound effectively enhanced gastric motility and gastric emptying in conscious dogs by oral administration (1-3 mg/kg).