1783-84-2 Usage
Description
Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω?6 fatty acid. In physiological literature, it is given the name 20:3 (ω?6). DGLA is a carboxylic acid with a 20-carbon chain and three cis double bonds; the first double bond is located at the sixth carbon from the omega end. DGLA is the elongation product of γ-linolenic acid (GLA; 18:3, ω?6). GLA, in turn, is a desaturation product of linoleic acid (18:2, ω?6). DGLA is made in the body by the elongation of GLA, by an efficient enzyme which does not appear to suffer any form of (dietary) inhibition. DGLA is an extremely uncommon fatty acid, found only in trace amounts in animal products.
Chemical Properties
Clear Colourless Oil
Uses
Different sources of media describe the Uses of 1783-84-2 differently. You can refer to the following data:
1. cis-8,11,14-Eicosatrienoic acid is a fatty acid which has selective tumoricidal action.
2. cis-8,11,14-Eicosatrienoic acid may be used as an analytical reference standard for the determination of the analyte in plant species and biological matrices by chromatography-based techniques.
Definition
ChEBI: An icosatrienoic acid having three cis double bonds at positions 8, 11 and 14.
General Description
cis-8,11,14-Eicosatrienoic acid is an unsaturated fatty acid, present in various plant species including Echium Rauwolfii, Sisymbrium Irio, Rhytididelphus squarrosus (Hedw.) Warnst etc, which are of pharmaceutical interest.
Check Digit Verification of cas no
The CAS Registry Mumber 1783-84-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,8 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1783-84:
(6*1)+(5*7)+(4*8)+(3*3)+(2*8)+(1*4)=102
102 % 10 = 2
So 1783-84-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h8-9,11-12,14-15H,2-7,10,13,16-19H2,1H3,(H,21,22)/b9-8-,12-11-,15-14-
1783-84-2Relevant articles and documents
PROCESS FOR PREPARING AND PURIFYING FATTY ACIDS
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, (2011/08/21)
There is provided a process for purifying a fatty acid, which process comprises reacting a fatty acid with a lithium salt in a first solution and under conditions to allow formation of a precipitate of a lithium salt of the fatty acid; isolating the precipitate; dissolving the precipitate in a second solution followed by separation of the organic and aqueous layers so formed; and evaporating the organic layer to isolate the purified fatty acid. There is also provided a process for increasing the length of a fatty acid, and the use of a lithium salt to purify a fatty acid.
Delta6-desaturase genes and uses thereof
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, (2008/06/13)
The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 6 (i.e., “Δ6-desaturase”). In particular, Δ6-desaturase may be utilized, for example, in the conversion of linoleic acid to γ-linolenic acid and in the conversion of α-linolenic acid stearidonic acid. The polyunsaturated fatty acids produced by use of the enzyme may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
Desaturase genes and uses thereof
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, (2008/06/13)
The subject invention relates to the identification of genes involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “Δ5-desaturase”) and at carbon 6 (i.e., “Δ6-desaturase”) and to uses thereof. In particular, Δ5-desaturase may be utilized, for example, in the conversion of dihomo-γ-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). Delta-6 desaturase may be used, for example, in the conversion of linoleic (LA) to γ-linolenic acid (GLA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
