178323-78-9Relevant academic research and scientific papers
Protection, metalation, and electrophilic substitution of 5-methyl tetrazole
Huff, Bret E.,LeTourneau, Michael E.,Staszak, Michael A.,Ward, Jeffrey A.
, p. 3655 - 3658 (1996)
5-Methyl tetrazole was N-protected with the trityl group and deprotonated using n-BuLi. The resulting 5-methyl anion was trapped with a variety of electrophiles to provide 5-substituted tetrazoles in good yields. The trityl protecting group was readily removed using HCl in methylene chloride.
