Tetrahedron Letters p. 3655 - 3658 (1996)
Update date:2022-08-03
Topics:
Huff, Bret E.
LeTourneau, Michael E.
Staszak, Michael A.
Ward, Jeffrey A.
5-Methyl tetrazole was N-protected with the trityl group and deprotonated using n-BuLi. The resulting 5-methyl anion was trapped with a variety of electrophiles to provide 5-substituted tetrazoles in good yields. The trityl protecting group was readily removed using HCl in methylene chloride.
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(2003)Doi:10.1021/ja00343a039
(1983)
