17833-53-3

Basic information

• Product Name: N-METHYL-DL-ASPARTIC ACID
• Synonyms: DL-2-METHYLAMINOSUCCINIC ACID;(+/-)-2-(METHYLAMINO)SUCCINIC ACID;N-METHYL-DL-ASPARTIC ACID;METHYL ASPARTIC ACID;N-Mel-DL-Asp-OH;(±)-2-(Methylamino)succinic acid, NMA;rac-(S*)-2-(Methylamino)-4-hydroxy-4-oxobutanoic acid;rac-(S*)-2-(Methylamino)succinic acid
• CAS NO: 17833-53-3
• Molecular Formula: C₅H₉NO₄
• Molecular Weight: 147.13
• Product Categories: Amino acids methyl、ethyl、t-butyl series
• Mol File: 17833-53-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 258.2 °C at 760 mmHg
• Flash Point: 110 °C
• Appearance: /
• Density: 1.343 g/cm³
• Vapor Pressure: 0.0042mmHg at 25°C
• Refractive Index: 1.494
• Solubility: H2O: 25 mg/mL, clear, colorless
• CAS DataBase Reference: N-METHYL-DL-ASPARTIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: N-METHYL-DL-ASPARTIC ACID(17833-53-3)
• EPA Substance Registry System: N-METHYL-DL-ASPARTIC ACID(17833-53-3)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 17833-53-3(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline powder

InChI:InChI=1/C5H9NO4/c1-6-3(5(9)10)2-4(7)8/h3,6H,2H2,1H3,(H,7,8)(H,9,10)

Upstream product

• 144300-47-0 N-methylaspartic acid dimethyl ester 
• 923-06-8 bromosuccinic acid 
• 74-89-5 methylamine 
• 624-48-6 dimethyl cis-but-2-ene-1,4-dioate 
• 110-16-7 maleic acid 
• 108-31-6 maleic anhydride 

Downstream Products

• 6384-92-5 N-methyl-D-aspartate 

Relevant articles and documents

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METHOD FOR PREPARING AMIDE

The present invention provides a method for preparing amides, in which an amino acid ionic liquid is used as both a reaction medium and a catalyst to catalyze Beckman rearrangement of a ketoxime, so as to produce an amide. In the method, the rearrangement is conducted by catalyzing a ketoxime with an amino acid ionic liquid having the asymmetric property at a moderate reaction temperature during a short reaction time, so as to produce an amide without adding other catalysts such as concentrate sulfuric acid. The method has advantages such as avoiding corrosion in equipments with pipelines, the high conversion rate of ketoximes and the high selectivity of amides.

Substituted quinoxaline-2-ones as glutamate receptor antagonists

A novel series of substituted quinoxaline 2-ones useful as neuroprotective agents are taught. Novel intermediates, processes of preparation, and pharmaceutical compositions containing the compounds are also taught. The compounds are glutamate receptor antagonists and are useful in the treatment of stroke, cerebral ischemia, or cerebral infarction resulting from thromboembolic or hemorrhagic stroke, cerebral vasospasms, hypoglycemia, cardiac arrest, status epilepticus, perinatal asphyxia, anoxia, seizure disorders, pain, Alzheimer's, Parkinson's, and Huntington's Diseases.