178445-27-7

Upstream product

• 110-54-3 hexane 
• 501-53-1 benzyl chloroformate 
• 583-71-1 4-bromo-o-xylene 
• 69189-19-1 4-bromo-1,2-bis-bromomethyl-benzene 
• 127168-85-8 2-(p-toluenesulfonyl)-5-bromoisoindoline 
• 127168-84-7 5-bromoisoindoline 
• 919346-89-7 5-bromo-2,3-dihydro-1H-isoindole hydrochloride 

Downstream Products

• 1618083-57-0 benzyl 5-(2,3-dihydroxypropyl)isoindoline-2-carboxylate 
• 1618083-58-1 benzyl 5-(2-oxoethyl)isoindoline-2-carboxylate 
• 1618083-59-2 2-(2-benzyloxycarbonylisoindolin-5-yl)acetic acid 
• 1618083-60-5 tert-butyl 3-((2R)-2-((2-benzyloxycarbonylisoindolin-5-yl)acetamido)-2-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0^2,6]dec-4-yl)ethyl)-2-methoxybenzoate 
• 1618083-61-6 tert-butyl 3-((2R)-2-((isoindolin-5-yl)acetamido)-2-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0^2,6]dec-4-yl)ethyl)-2-methoxybenzoate 
• 1618090-65-5 tert-butyl 3-((2R)-[[2-[2-[(Z)-N,N'-bis(tert-butoxycarbonyl)carbamimidoyl]isoindolin-5-yl]acetyl]amino]-2-(2,9,9-trimethyl-3,5-dioxa-4-bora-tricyclo[6.1.1.0^2,6]dec-4-yl)ethyl)-2-methoxybenzoate 
• 1618083-56-9 benzyl 5-allylisoindoline-2-carboxylate 

Relevant academic research and scientific papers

NOVEL MORPHOLINYL AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE

The present invention relates to compounds of formula (I), wherein R1, R2 and R3 are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

NOVEL HETEROARYL HETEROCYCLYL COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE

The present invention relates to compounds of formula (I), ab (I), wherein R1 to R3 and L are as described herein, and their pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.

BETA-LACTAMASE INHIBITORS

Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Quinolonecarboxylic acid derivatives or salts thereof

PCT No. PCT/JP97/00317 Sec. 371 Date Aug. 10, 1998 Sec. 102(e) Date Aug. 10, 1998 PCT Filed Feb. 7, 1997 PCT Pub. No. WO97/29102 PCT Pub. Date Aug. 14, 1997The present invention relates to a quinolone-carboxylic acid derivative represented by the general